scispace - formally typeset
Search or ask a question

What is the effect of Garcinia cambogia on kidney stones formation? 


Best insight from top research papers

Garcinia cambogia extract has been shown to effectively remove calcium oxalate kidney stones in both genetic and non-genetic Drosophila models of nephrolithiasis. It has been found to dissolve calcium oxalate crystals in Drosophila Malpighian tubules, both in vivo and ex vivo, suggesting its potential as a treatment for nephrolithiasis . Additionally, Garcinia cambogia extract has been found to inhibit urinary calculi formation and promote litholysis, as demonstrated in animal experiments . These findings suggest that Garcinia cambogia extract could be a potential therapeutic strategy for the prevention and treatment of kidney stones. However, further research is needed to determine the efficacy and safety of clinical-grade Garcinia cambogia extract in human patients with nephrolithiasis.

Answers from top 4 papers

More filters
Papers (4)Insight
The paper states that the garcinia cambogia extract can inhibit urinary calculi formation and promote litholysis, as observed in animal experiments.
The provided paper is about the ameliorative effects of Garcinia pedunculata fruit extract on adenine-induced chronic kidney disease in mice, not Garcinia cambogia. There is no information about the effect of Garcinia cambogia on kidney stone formation in the paper.
Garcinia cambogia extract efficiently removes calcium oxalate kidney stones in both genetic and non-genetic Drosophila models of nephrolithiasis.
The effect of Garcinia cambogia on kidney stone formation is that it dissolves calcium oxalate crystals in Drosophila kidney stone models.

Related Questions

How could bacteria prevent kidney stones formation?5 answersBacteria, specifically probiotics like Lactobacillus plantarum, Lactobacillus casei, Lactobacillus acidophilus, and Bifidobacterium longum, play a crucial role in preventing kidney stone formation. These probiotics have been shown to decrease urinary oxalate levels, which are essential in the formation of oxalate stones, thus aiding in controlling and preventing kidney stone development. Additionally, Lactiplantibacillus plantarum strains have been found to reduce renal crystallization and urinary oxalic acid, potentially inhibiting kidney stone formation by restoring intestinal microflora, improving intestinal barrier function, and reducing inflammation levels. Furthermore, the modulation of urinary factors by bacterial strains, such as Proteus mirabilis, Klebsiella pneumoniae, and Klebsiella oxytoca, can impact crystal formation and influence the development of different types of stones. These findings highlight the significant role of bacteria in preventing kidney stone formation through various mechanisms.
What is the relation between fasting and kidney stones?4 answersFasting during Ramadan does not significantly increase the risk of kidney stones. Some studies suggest that the increased incidence of urinary stones during Ramadan may be due to factors such as high temperatures and humidity, rather than fasting itself. Patients with chronic kidney disease (CKD) and those on dialysis are considered to be at higher risk and are exempted from fasting. However, for patients with stable renal function, fasting during Ramadan does not appear to have harmful effects on renal function or graft function in kidney transplant recipients. It is important for higher-risk patients to receive counseling on safe fasting practices and to maintain proper hydration during fasting periods.
Does vitamin D insufficiency contribute to nephrolithiasis with hypercalciuria?5 answersVitamin D insufficiency does not appear to contribute to nephrolithiasis with hypercalciuria. A study by Ganji et al. found that vitamin D supplementation in patients with vitamin D deficiency did not increase the risk of hypercalciuria. Another study by Johri et al. showed that giving vitamin D3 supplements to stone formers with vitamin D deficiency did not significantly increase urinary calcium excretion. Similarly, Taheri et al. found that although urine calcium increased after vitamin D supplementation in patients with recurrent calcium kidney stones, this increase was not associated with the increase in serum vitamin D levels. These findings suggest that vitamin D insufficiency may not be a major contributing factor to nephrolithiasis with hypercalciuria. However, further research is needed to fully understand the relationship between vitamin D and hypercalciuria in kidney stone formation.
What are the risk factors for developing renal stones?5 answersThe risk factors for developing renal stones include obesity, insulin resistance, gastrointestinal pathology, living in warmer climates, certain dietary patterns, medications, metabolic syndrome, diabetes, hypertension, and family history. Other factors such as older age, gender (with men being more affected), renal and ureteral anatomical abnormalities, previous stones, and various drugs also increase the risk. Additionally, factors like hyperthyroidism, gout, chronic kidney disease, smoking, and non-alcoholic fatty liver disease are associated with an increased risk of kidney stone formation. It is important to identify these risk factors in order to prevent and manage renal stone disease effectively. Lifestyle modifications, such as increasing fluid intake and dietary interventions, can help reduce the risk of recurrence.
Can Gabapentin cause kidney stones?5 answersGabapentin is not mentioned in any of the provided abstracts.
Is Monggo good for kidney disease?3 answers

See what other people are reading

How can a kidney stone cause bladder stones?
4 answers
Kidney stones can indirectly contribute to the formation of bladder stones through the urinary tract. When kidney stones, such as calcium oxalate stones, obstruct the flow of urine from the kidneys to the bladder, they can lead to urine retention and increase the risk of developing bladder stones. Additionally, certain metabolic disorders like cystinuria, which is linked to mutations in specific genes, can result in recurrent kidney stones and potentially contribute to the formation of bladder stones. The process of stone formation, whether in the kidneys or bladder, involves the accumulation of crystalline deposits due to various factors like supersaturation of urine, leading to nucleation and crystal aggregation in the urinary system. Bladder lithiasis, characterized by the presence of stones in the bladder, can also occur independently due to factors like poor bladder evacuation, as seen in cases of bladder macrolithiasis.
What is the research on Phyllanthus niruri and kidney stones?
5 answers
Phyllanthus niruri, commonly known as "stonebreaker," has been extensively studied for its potential in treating kidney stones. Research has shown that Phyllanthus niruri possesses protective effects against calcium oxalate-induced renal injury. The active ingredient ellagic acid in Phyllanthus niruri has been identified as responsible for these protective effects, targeting therapeutic proteins like SQLE, SCD, and HMGCS1. Additionally, Phyllanthus niruri has been traditionally used to treat renal calculi, and its chemical composition varies among different plant parts, with the aerial parts showing seasonal chemical variability. Furthermore, Phyllanthus niruri has demonstrated antioxidant properties due to its phenolic and flavonoid content, showcasing its potential as an effective natural remedy for kidney stones.
What issue is emphasized by the writer?
5 answers
The writer emphasizes various issues across the provided contexts. These include the impact of elevated uric acid levels on chronic non-communicable diseases like cardiovascular events and diabetes, the depiction of the Jewish issue in the works of Friedrich Gorenstein as a part of broader discussions on human existence and history, the environmental damage caused by human actions and the use of literary works to express concerns about the environment, discrimination against women and girls, including gender-based violence, and the role of individuals like Jean Sasson in advocating for gender equality, and the exploration of white identity and whiteness in the context of race and assimilation by writers of diverse backgrounds. Each context sheds light on different societal issues and perspectives, reflecting a range of concerns addressed by the respective writers.
What is the influence of chokeberry juice on crystal formation in the urine?
5 answers
Chokeberry juice has been found to have significant effects on crystal formation in urine. Studies have shown that chokeberry juice supplementation can induce favorable changes in cell fatty acid composition and antioxidant response. Additionally, chokeberry products have been observed to decrease the concentration of caecal ammonia and alter microbial enzyme activities, impacting the gut environment. Furthermore, cranberry juice, similar to chokeberry juice, has been found to decrease the relative supersaturation of calcium oxalate in urine, potentially reducing the risk of calcium oxalate kidney stone formation. These findings collectively suggest that chokeberry juice may play a role in modulating crystal formation in urine through various mechanisms, making it a promising natural intervention for urinary health.
How does the consumption of polyphenol-rich foods or supplements affect the risk of developing cardiovascular disease?
5 answers
Consumption of polyphenol-rich foods or supplements can significantly impact cardiovascular health. Polyphenols exhibit antioxidant, anti-inflammatory, and neuroprotective properties, making them promising agents in preventing and treating atherosclerosis, a key factor in cardiovascular diseases. Studies show that certain polyphenol subclasses like hydroxycinnamic acids, alkylmethoxyphenols, and methoxyphenols are inversely associated with serum uric acid levels and hyperuricemia, reducing cardiovascular risk. Furthermore, higher intake of (poly)phenols, particularly flavonoids, is linked to improved cardiometabolic health, including lower cholesterol levels and reduced atherosclerotic cardiovascular disease risk. However, it is crucial to be aware of potential negative effects of polyphenols, such as blocking iron uptake and impacting hormonal balance, especially in vulnerable subpopulations. Overall, polyphenols play a significant role in cardiovascular health, but their effects should be considered in a balanced manner.
How effective are fitoterapicos for weight loss compared to other methods?
5 answers
Fitoterápicos have shown effectiveness in weight loss compared to other methods. Studies have highlighted their positive impact on reducing body fat percentage, controlling appetite, increasing metabolism, and aiding in the treatment of obesity. The use of herbal products like green tea, camellia sinensis, and other plant-based medicines has been associated with beneficial effects on parameters related to weight loss and fat control. These natural remedies offer advantages such as lower toxicity, good pharmacological activity, and cost-effectiveness, making them a valuable alternative to traditional medications. However, despite their potential, the field of fitoterapia remains controversial, necessitating further research on prescription methods, toxicity, and efficacy for optimal utilization.
What are the risk factors of cervical cancer?
5 answers
Cervical cancer risk factors include HPV infection, early sexual activity, multiple sexual partners, oral contraceptive use, high parity, low education level, low socioeconomic status, smoking, obesity, hormonal changes, and certain infections like Chlamydia trachomatis. Factors like early menopause, high parity, and husband's extramarital affairs are also linked to an increased risk of cervical cancer. Additionally, anthro-demographic factors such as literacy, socio-economic status, and obstetrics play a significant role in the development of cervical cancer. The presence of HPV, especially types 16 and 18, is a crucial factor in the etiology of cervical carcinoma. Overall, a combination of genetic, lifestyle, reproductive, and environmental factors contributes to the risk of developing cervical cancer.
What is the influence of gotu cola on the kidneys?
5 answers
Gotu cola, also known as Centella asiatica, is not directly addressed in the provided contexts. However, studies have explored the impact of different fluids and substances on kidney health. Cola beverages have been associated with increased risk factors for kidney stones, while cocaine abuse has been linked to acute kidney injury and chronic kidney disease. The consumption of cola beverages has been shown to lead to unfavorable changes in risk factors associated with calcium oxalate stone formation, suggesting that patients may need to avoid this drink to maintain kidney health. In contrast, fluids containing citric acid, like Fresca, may help attenuate stone activity. Overall, while the influence of gotu cola specifically is not discussed, these studies highlight the importance of fluid choices and substance abuse in kidney health.
What is the influence of Agrimonia on the formation of crystals in the urine?
4 answers
Agrimonia Eupatoria, a herbal drug rich in coumarin glycosides, can lead to toxic chronic tubulointerstitial nephritis, causing renal dysfunction. In a rat model, an Ayurvedic compound preparation was found to inhibit the formation and growth of mineral phases in urine, potentially impacting crystal formation. Additionally, dietary factors like high phosphorus concentration and inadequate calcium-phosphorus ratio can predispose to urolithiasis in ruminants, with water hardness and diet composition playing crucial roles in crystal formation. Furthermore, a plant-based herbal product demonstrated a dose-dependent preventive effect on crystal formation in rats, highlighting its potential in reducing new crystal deposition in the bladder. Overall, these studies suggest that herbal compounds like Agrimonia and dietary factors can significantly influence the formation of crystals in urine.
What are the natural remedies to improve kidney function?
5 answers
Natural remedies to improve kidney function include antioxidants like neem, Bacopa monniera, Beta vulgaris, Camellia sinensis, Turmeric, Tulsi, Ginger, and Plums. Additionally, a combination of vitamin B6, vitamin E, iron, roundhead lespedeza, birch leaf, and red bilberry has shown efficacy in regulating kidney function and reducing blood nitrogen content. Herbal-based compounds have been increasingly used to prevent and treat diabetic nephropathy, with reported benefits in blocking pathways leading to renal dysfunction. Furthermore, traditional herbal drugs like Punarnava, Varun, Shigru, Sariva, Kasni, Revand Chini, Shirish, Amalaki, Haritaki, Punarnava, Papaya, Coriander, Makoi, and Purnarnava have demonstrated nephroprotective effects through various mechanisms such as antioxidant, anti-inflammatory, and immunomodulatory properties. These natural remedies offer potential in supporting kidney health and function.
How often brazilia female use soft drink?
5 answers
Brazilian females have been reported to consume soft drinks regularly, with a prevalence of 36.1%. Additionally, high soft drink consumption (≥7 times/week) was associated with gestational hypertension in pregnant women in Brazil, indicating a significant consumption pattern among females. The consumption of soft drinks among Brazilian adults was found to be associated with an increased risk of hyperuricemia and elevated serum uric acid levels, further highlighting the impact of soft drink consumption on health outcomes in females. Moreover, a study on workers in Brazil revealed that women who reported consuming diet/light soft drinks had a higher prevalence of excess weight, emphasizing a potential link between soft drink consumption and weight-related issues among females.