scispace - formally typeset
Search or ask a question

What is the epidemiology of leishmaniasis? 


Best insight from top research papers

Leishmaniasis is a neglected tropical disease caused by protozoan parasites of the genus Leishmania, transmitted by female sand-fly vectors. It has various clinical manifestations, including cutaneous leishmaniasis (CL), visceral leishmaniasis (VL), and mucocutaneous leishmaniasis. The disease is highly correlated with poverty, malnutrition, and poor sanitation. Risk factors for leishmaniasis include immunocompromised hosts, crowded living conditions, and malnutrition. Diagnostic procedures for leishmaniasis include serological tests such as ELISA and rK-39, as well as clinical examination. Treatment options include antimony-based drugs, Liposomal Amphotericin-B, Miltefosine, Paromomycin, Pentamidine, and Sitamaquine. Drug resistance is a major problem, particularly with antimony-based drugs. The incidence of leishmaniasis varies by region, with higher rates observed in endemic areas. The disease affects individuals of all ages, with a higher incidence in children and males. The epidemiology of leishmaniasis is influenced by factors such as climate change, migration, and changes in the notification system.

Answers from top 5 papers

More filters
Papers (5)Insight
Cutaneous leishmaniasis is an endemic disease in Al-Ramadi, Iraq, with a prevalence rate of 59/100,000. It mainly affects individuals younger than 20 years, with a higher incidence during the winter months. The most commonly involved sites are the hands, face, and feet.
The paper provides information on the prevalence of leishmaniasis in different regions of Khyber Pakhtunkhwa, Pakistan, with the highest incidence observed in North Waziristan. It also mentions that the majority of infected patients were males and children under 10 years old.
Book ChapterDOI
01 Jan 2023
The paper provides information on the epidemiology of leishmaniasis, including the main risk factors such as malnutrition, poor sanitation, and living conditions, as well as immunocompromised hosts.
The paper provides information on the epidemiology of leishmaniasis, including its transmission by sand-fly vectors and its correlation with poverty, malnutrition, and environmental factors.

Related Questions

What is the epidemiology of leptospirosis worldwide for year 2013 to 2023?5 answersLeptospirosis is a worldwide zoonotic disease that has emerged and re-emerged in many countries. The epidemiology of leptospirosis varies between regions and time periods due to factors such as animal husbandry practices, climate, and human behavior. Studies have been conducted in various countries, including the Middle East, India, and worldwide, to understand the prevalence and seroprevalence of leptospirosis. The disease has been reported in different hosts, including domestic cats and unconventional hosts such as Carnivora, Didelphimorphia, Rodentia, Cetacea, and Primate orders, as well as Reptilia and Amphibia classes. The predominant serogroups identified in these studies include Sejroe, Grippotyphosa, Icterohaemorrhagiae, Autumnalis, and Pomona. Diagnostic tests such as the microscopic agglutination test (MAT) and isolation of Leptospira strains have been used to detect infections. Antibiotics such as doxycycline, azithromycin, penicillins, and third-generation cephalosporins are used for treatment. Public education, vaccination, rodent control, and improved environmental hygiene are important intervention strategies.
What is the epidemiology of human leptospirosis worldwide for year 2013 to 2023?5 answersLeptospirosis is a significant worldwide zoonotic disease that causes economic and social damage. The epidemiology of leptospirosis varies between countries and regions. Studies have been conducted in various Middle Eastern countries, such as Iran, Turkey, and Egypt, to understand the epidemiological situation of leptospirosis in the region. Leptospira strains have been isolated from a wide range of animal species, including Carnivora, Rodentia, Cetacea, and Primate orders, as well as Reptilia and Amphibia classes. Leptospirosis is a re-emerging infectious disease with a higher incidence in tropical regions. Changes in animal husbandry, climate, and human behavior have modified the epidemiology of leptospirosis. Leptospirosis is prevalent in low-income and middle-income countries, particularly in tropical and subtropical regions. However, there is a lack of documented evidence on the specific risk factors, symptoms, and mortality associated with leptospirosis coinfections with other pathogens.
What are Epidemiology Lyme disease?5 answersLyme disease is a zoonosis caused by the spirochete Borrelia burgdorferi and its genospecies. It is transmitted to humans through tick bites, primarily from the tick Ixodes ricinus in Europe and Ixodes pacificus in North America. The disease has a wide range of clinical manifestations, with the most common symptom being a skin rash called erythema migrans. The epidemiology of Lyme disease has evolved over the years, with the establishment of public health surveillance systems and the development of case definitions to facilitate diagnosis and reporting. Incidence rates vary across different populations, with higher rates observed in certain age groups and geographic regions. Surveillance and modeling efforts have also provided insights into the distribution and infection rates of ticks carrying the Borrelia burgdorferi bacteria. Further research is needed to better understand the ecology and epidemiology of Lyme disease, particularly in western North America.
What is the epidemiology of the ebola virus?5 answersThe epidemiology of the Ebola virus involves the occurrence and distribution of outbreaks. Since its discovery in 1976, there have been 32 outbreaks resulting in nearly 15,350 deaths in more than ten African countries. The largest outbreaks occurred in West Africa from 2013 to 2016 and in the Democratic Republic of the Congo from 2018 to 2020. The virus is zoonotic, with natural hosts and secondary reservoirs still unknown. The disease has high mortality and strong infectivity, making it a global public health threat. The outbreaks have shown an increase in the geographical extent and population at risk, but a decrease in case fatality rate over time. Effective outbreak control requires a multidisciplinary approach, including case management, infection prevention and control practices, surveillance, and contact tracing. Advances in diagnostic technologies, viral characterization, and new treatments and vaccines have been made.
What is the epidemiology of leprosy in world?5 answersLeprosy is a bacterial infection that has been affecting humanity for thousands of years and is considered a neglected tropical disease. Despite efforts to control the disease, it remains a major healthcare concern in underdeveloped and developing countries like India and Brazil. Leprosy was declared "eliminated" as a global public health problem by the World Health Organization in 2000, but there were still approximately 200,000 new cases reported worldwide in 2017. The target of eliminating leprosy as a public health problem was reached in 2000 at the global level, but there was no decline in the number of new cases detected. Globally, new case detection of leprosy has seen a gradual decline since 2004-2005, except in India where there has been a sharp decline since 2001. The leprosy elimination goal set by the World Health Organization was achieved in 2000, but more than 200,000 new cases are still reported each year, particularly in India, Brazil, and Indonesia.
What is the epidemiology of human rabies?5 answersHuman rabies is a fatal and acute zoonotic disease that is prevalent worldwide. The majority of human exposures to the rabies virus are caused by dog bites. The disease is endemic in many countries, with the highest mortality rates reported in Asia and Africa. The transmission of rabies occurs through the saliva of infected animals, primarily through bites. Diagnosis of rabies is mainly based on clinical signs and symptoms, history of exposure, and vaccination prophylaxis. The epidemiology of human rabies has shown changes over time, with recent outbreaks reported in different regions, including Bali and China. Surveillance and diagnostic infrastructure in developed countries have provided insights into changing patterns of rabies epidemiology, which can be relevant to less-developed nations. Rabies prevention and control strategies include post-exposure prophylaxis, vaccination, and effective management of dog populations.