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The cost of detecting a mutation within a population of women is highly dependent on the prevalence of the mutation in the population.
Constituent ratio of the treatment fee and constituent ratio of the inspection and laboratory fee increased for both samples, except for the constituent ratio of the inspection and laboratory fee of quota payment diseases in 2016, which did not change. Quota payment for specific diseases under global budget had obviously positive effects on cost control in Weiyuan, Gansu.
This high cost is due, in part, to the fact that many mutation operators generate redundant mutants that may both misrepresent the mutation score and increase the runtime of the mutation analysis process.
The overall mutation density was estimated and it resulted to be 1/322 kb and 1/574 kb for the 1% EMS and 0.7% EMS treatment respectively. The mutation density estimated in our collection and its comparison with other TILLING populations demonstrate that the Red Setter genetic resource is suitable for use in high-throughput mutation discovery.
This implies that phenotypic markers give a more precise view of mutation rate than previously believed: having accounted for other known factors affecting mutation rate, controlling for population density can reduce variation in mutation-rate estimates by 93%.
Open accessJournal ArticleDOI
Kayla M. Peck, Adam S. Lauring 
253 Citations
This is due, in part, to their high mutation rates.
It provides the ground realities of the incidence of indebtedness in Medak, one of the most distressed districts of Telangana, a Southern Indian state.
That is an urgent need that the Telangana Government should look in the matter with all sympathy and concern.
This study is the first of its kind in rural Telangana.
Open accessJournal ArticleDOI
Yunxin Fu, Haying Huai 
01 Jun 2003-Genetics
20 Citations
We show in this article that counting mutant individuals is a correct approach for estimating mutation rate, while counting only mutation events will result in underestimation.