What is the frontier of knowledge in the use of exosomes in glioblastoma?
Best insight from top research papers
The frontier of knowledge in the use of exosomes in glioblastoma lies in their role as potent carriers for targeted therapy and diagnostic markers. Exosomes, being small extracellular vesicles, facilitate intercellular communication and play crucial roles in tumor progression, immune tolerance, and drug resistance in gliomas. They are explored for their ability to deliver drugs effectively across the blood-brain barrier, a significant challenge in glioblastoma treatment. Moreover, exosomes are rich in biomolecules like proteins, nucleic acids, and microRNAs, making them valuable sources of diagnostic and prognostic markers for glioblastoma. The ongoing research focuses on harnessing exosomes' inherent properties for developing precise and biocompatible therapeutic strategies, marking a promising avenue in the emerging era of precision medicine.
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| Papers (5) | Insight |
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07 Jun 2023 | Exosomes, containing CD44, VEGFA, TGFβ1, THBS1, and SERPINE1, serve as early non-invasive predictors of disease state in differentiating high-grade from low-grade glioblastomas, particularly in blood serum samples. |
| Exosomes are explored as potential biomarkers for diagnosis, disease progression, and as delivery platforms for glioblastoma treatment, showcasing a frontier in precision medicine and targeted therapy. | |
| Exosomes serve as promising non-invasive drug delivery tools to overcome the blood-brain barrier and target glioblastoma cells effectively, representing a frontier in glioblastoma therapy. | |
| Exosomes in gliomas play a crucial role in tumor progression, immune evasion, and drug resistance. They offer potential as diagnostic biomarkers and drug delivery systems, advancing glioblastoma research and therapy. | |
| Exosomes serve as promising drug carriers for treating glioblastoma due to their cell-targeting properties, stability, and potential diagnostic markers, advancing targeted therapy in GBM treatment. |
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