What is the role of nitrosamines in organic chemistry reactions?
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Nitrosamines play a significant role in organic chemistry reactions, particularly in the formation of nitrosation reactions and other important chemical transformations. They are known for their ability to induce nitrosation reactions either within the same molecule or with other molecules or solvents . Nitrosamines are reactive organic chemicals that can be found in various consumer products, processed foods, and even pharmaceutical preparations, often arising as impurities from production processes or degradation . These compounds are formed by the reaction of nitrates or nitrites with certain amines and are considered strong carcinogens, capable of inducing cancer in various organs and tissues . Understanding the chemistry, structure, and reactivity of nitrosamines, especially alkyl N-nitrosamines, is crucial for addressing challenges related to their prevention, detection, and remediation .
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01 Jan 2004 2 Citations | Nitrosamines play a crucial role in nitrosation reactions, affecting molecules and sites within the same molecule. They are known carcinogens, sparking significant research interest in their occurrence and effects. |
31 Citations | Not addressed in the paper. |
5 Citations | Nitrosamines in organic chemistry reactions can lead to DNA alkylation through a series of activation steps, influenced by steric and electronic factors, ultimately forming carcinogenic carbenium ions. |
| Nitrosamines in organic chemistry reactions are formed by the reaction of nitrates/nitrites with amines, found in processed foods, alcoholic beverages, and cigarette smoke, and are potent carcinogens. | |
50 Citations | Nitrosamines play a significant role in organic chemistry reactions due to their structure, reactivity, and synthetic applications, particularly focusing on alkyl N-nitrosamines. |
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