What is the role of oxytocin in food intake regulation?
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Oxytocin plays a role in the regulation of food intake. It limits meal size through interactions in key brain regions involved in the control of food intake, such as the hypothalamus and hindbrain . Oxytocin also affects feeding reward areas, such as the nucleus accumbens and ventral tegmental area . It has been found to reduce consumption of carbohydrates and sweet tastants . Oxytocin's effects on food intake are not solely due to reductions in food intake, but also involve changes in lipolysis, energy expenditure, and glucose regulation . Peripheral administration of oxytocin mimics its effects when given centrally, suggesting a role for circulating oxytocin in energy balance regulation . Oxytocin has shown promising results in reducing body mass in animal models and in humans in other areas of research . However, the use of oxytocin in the clinical setting to combat obesity and overeating has generated mixed results .
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| Papers (5) | Insight |
|---|---|
| The neuropeptide oxytocin regulates food intake by limiting meal size through interactions in key brain regions such as the hypothalamus and hindbrain. | |
| The paper does not explicitly discuss the role of oxytocin in food intake regulation. | |
6 Citations | The role of oxytocin in food intake regulation is to limit meal size through interactions in key brain regions governing the control of food intake and feeding reward areas. It also affects lipolysis, energy expenditure, and glucose regulation. |
8 Citations | The role of oxytocin in food intake regulation is to reduce food intake by amplifying within-meal physiological satiation signals, rather than altering between-meal interoceptive hunger and satiety states. |
| The role of oxytocin in food intake regulation is to reduce food intake, suppress activation of food motivation brain areas, and increase activation of self-control brain regions. |
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What is oxytocin?5 answersOxytocin is a hormone that has diverse functions in the body. It is produced in the hypothalamus and stored in the neurohypophysis. Initially, oxytocin was associated with female reproduction, specifically labor, breastfeeding, and maternal behavior. However, it is now known that oxytocin has a wider range of effects in both sexes. It functions as both an endocrine hormone and a local signaling molecule, with additional peripheral sites of secretion and an extensive receptor apparatus. Oxytocin has been shown to have various physiological effects, including its role in social and sexual behavior, protection from stress, reproduction, metabolism, and bone growth. It is also involved in the regulation of eating behavior and social behavior through its interaction with the gut microbiota and the brain-gut axis. Oxytocin plays a crucial role in the milk ejection reflex and is involved in attachment and prosocial behaviors.
Does oxytocin have any effect on the health benefits of cow milk?4 answersOxytocin has been found to have significant effects on the protein and fatty acid profiles of cow milk during different lactation stages. Oxytocin injection resulted in lower intensity bands of casein and whey protein fractions in milk compared to the control group. Additionally, oxytocin-treated milk showed reductions in the concentrations of fatty acids C16:0 and C18:1 compared to the control group. However, it should be noted that oxytocin use in dairy animals does not seem to have any harmful effects on humans consuming the milk, as oxytocin is degraded by gut enzymes and does not reach the bloodstream in biologically active form. Therefore, while oxytocin may have an impact on the composition of cow milk, it does not appear to affect the health benefits of the milk for human consumption.
What is the impact of oxytocin contaminated milk ingestion on pregnant women?5 answersThe impact of oxytocin contaminated milk ingestion on pregnant women is not explicitly mentioned in the provided abstracts. However, one study analyzed the occurrence of oxytocin residues in milk samples and found that nonbranded milk samples had a higher prevalence of oxytocin residues compared to branded milk samples. The average daily intake of oxytocin was found to be 0.087 μg per person. It was concluded that the concentration of oxytocin was relatively higher in samples obtained from dairy farms, dairy shops, and milkmen compared to ultra-high temperature (UHT) and powder milk samples. Another study investigated the milk-ejecting effect induced by oxytocin during human pregnancy and found that the milk-ejecting effect induced by oxytocin is 40 to 50 times greater than that of vasopressin. However, there is no specific information about the impact of oxytocin contaminated milk ingestion on pregnant women in the provided abstracts.