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What is the role of THCAS lysate in the synthesis of cannabinoids? 


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THCAS lysate plays a role in the synthesis of cannabinoids by providing a platform for the production of cannabigerolic acid (CBGA) and cannabichromenic acid (CBCA), which are precursors to various cannabinoids. The lysate system utilizes enzymes from Cannabis sativa, such as aromatic prenyltransferase (AtaPT) and THCAS promoter regulatory region , to produce CBGA and CBCA. These compounds can then be further converted into cannabinoids like cannabigerol (CBG) and cannabichromene (CBC) . The lysate system allows for the sustainable production of cannabinoids in an Escherichia coli chassis . Additionally, rational design approaches and computational analyses can be used to enhance the catalytic efficiency of enzymes involved in the biosynthesis of CBCA, leading to increased production of CBCA and cannabinoids .

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Patent
Robert Winnicki, Marc Donsky 
27 Feb 2014
19 Citations
The provided paper does not mention the role of THCAS lysate in the synthesis of cannabinoids.
The provided paper does not mention the role of THCAS lysate in the synthesis of cannabinoids.
The provided paper does not mention the role of THCAS lysate in the synthesis of cannabinoids. The paper focuses on the identification and characterization of three novel transcription factors involved in cannabinoid biosynthesis in Cannabis sativa L.
The provided paper does not mention the role of THCAS lysate in the synthesis of cannabinoids. The paper focuses on improving the catalytic efficiency of CBCA synthase, a different enzyme involved in the biosynthesis of cannabichromenic acid (CBCA).
The provided paper does not mention the role of THCAS lysate in the synthesis of cannabinoids.

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