What is Transthoracic needle aspiration (TTNA)?
Best insight from top research papers
Transthoracic needle aspiration (TTNA) is a safe and accurate diagnostic procedure used for obtaining tissue samples from peripheral lung nodules. It involves using a needle guided by computed tomography (CT) to biopsy the lung tissue . TTNA has been shown to have a high accuracy rate for tissue diagnosis, with a low rate of complications . It is particularly useful for obtaining suitable samples for molecular testing in lung adenocarcinomas, allowing for the identification of genetic mutations and targeted oncological therapy . TTNA is a minimally invasive technique that provides excellent sensitivity, specificity, and predictive diagnostic values for evaluating the mediastinum and staging patients with lung cancer . It can be performed in conjunction with other procedures, such as endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), to achieve a comprehensive evaluation of the mediastinum in a minimally invasive manner . TTNA is also effective in diagnosing mediastinal lesions and can be used to obtain cytological specimens for ancillary testing, such as immunohistochemistry and tumor genotyping .
Answers from top 4 papers
More filters
| Papers (4) | Insight |
|---|---|
Open access•Journal Article | TTNA is a diagnostic procedure used in pulmonary nodules when bronchoscopy is not feasible. It involves percutaneous aspiration of cytological samples from the lung lesions. |
48 Citations | The provided paper does not mention Transthoracic needle aspiration (TTNA). |
59 Citations | The provided paper does not mention Transthoracic needle aspiration (TTNA). |
4 Citations | Transthoracic needle aspiration (TTNA) is not mentioned in the provided paper. |
Related Questions
What is th?4 answersThyroid hormone (TH) is a multifaceted entity with diverse implications. It serves as a pivotal modulator in biological processes across species, playing a crucial role in development, metabolism, and response to environmental stimuli. TH influences cellular energy metabolism, triggering reactive oxygen species generation and redox signaling, which in turn protect cells through various mechanisms. Additionally, TH can be viewed as a test harness facilitating the development of scientific software by comparing results from different versions of an application code to ensure equivalence, with the flexibility to be activated or deactivated as needed. Furthermore, TH has been historically linked to philosophical ideologies, symbolizing a transformative force akin to a radical revolution through technological advancements.
What is Pulmonary sarcoidosis?4 answersPulmonary sarcoidosis is a form of sarcoidosis, an inflammatory disease of unknown cause characterized by the formation of noncaseating granulomas. It predominantly affects the lungs and intrathoracic lymph nodes, leading to granulomatous inflammation in these organs. The disease is highly heterogeneous, often asymptomatic, but can progress to chronic or severe states in up to one-third of patients, mainly due to pulmonary or cardiovascular complications. Treatment typically involves oral glucocorticoids as first-line therapy, with immunosuppressive agents considered for those with inadequate response or intolerable side effects. The diagnosis of pulmonary sarcoidosis is based on clinical symptoms, histopathological evidence of granulomatous inflammation, and exclusion of other causes of granulomatous disorders.
What is pneumothorax?5 answersPneumothorax is the accumulation of air in the pleural space, leading to lung collapse and breathing difficulties. It can be spontaneous, traumatic, or iatrogenic, with causes like lung rupture, fractured ribs, or medical procedures. Diagnosis often involves thoracic radiography or advanced techniques like deep learning models for accurate detection. Management may include thoracocentesis, IV catheter placement, or surgical interventions like video-assisted thoracoscopic surgery (VATS). Pneumothorax can present with symptoms such as chest pain, shortness of breath, and rapid breathing, emphasizing the importance of early diagnosis and treatment. Advanced technologies and evolving surgical approaches play crucial roles in improving outcomes for patients with pneumothorax.
What is mediastinal infection in throat?4 answersMediastinal infection in the throat refers to a deep thoracic infection that occurs as a result of prolonged oropharyngeal or odontogenic infections such as pharyngitis, tonsillitis, and dental caries. It is a serious and potentially fatal condition known as descending necrotizing mediastinitis (DNM). The most common pathogens involved in this type of infection are Gram-positive cocci and anaerobes. Patients with mediastinal infection in the throat often have underlying medical conditions such as diabetes mellitus, steroid use, and chronic renal failure. Surgical drainage is necessary for treatment, and it should be performed as soon as possible after diagnosis. The mortality rate of DNM has improved in recent years, but it still remains high. Prompt commencement of broad-spectrum antibiotics combined with surgical drainage is crucial to limit further spread of infection.
What is TPACK?4 answersTPACK (Technological Pedagogical Content Knowledge) is a framework that integrates technology, pedagogy, and content knowledge in education. It is important for teachers to have TPACK knowledge to effectively deliver instruction with the integration of technology. TPACK helps teachers in designing lesson plans, preparing teaching materials, and assessing student learning. It is a professional knowledge framework that provides a new cognitive framework for teachers' knowledge construction. TPACK assists teachers in developing technology-based learning content and implementing strategies to help students understand the material. In the context of vocational education and training, an adapted TPACK framework, known as N-TPACK, includes networking and collaborative knowledge as an essential aspect of professional knowledge for vocational teachers. Overall, TPACK is a comprehensive framework that guides teachers in effectively integrating technology into their teaching practices.
What is pneumovirus?5 answersPneumovirus is a family of viruses that infect the respiratory tract of their host species. The most well-known pneumoviruses are respiratory syncytial virus (RSV) and human metapneumovirus (hMPV). These viruses have a non-segmented negative-sense RNA genome and replicate in specialized cytosolic organelles called inclusion bodies (IB). The replication process involves the transport of newly synthesized nucleocapsids from IBs to assembly sites, potentially via the actin cytoskeleton. The released virions, which generally contain one genome, can then diffuse in the extracellular environment to infect new cells. Pneumoviruses have mechanisms that allow for the transmission of multiple genomes at the same time, including syncytia formation and the formation of long actin-based intercellular extensions. Despite the public health burden caused by pneumoviruses, there are currently no approved vaccines for RSV or hMPV.