What literature is there regarding experimental treatment of ARMs?
Best insight from top research papers
Experimental treatment of ARMs has been studied in several papers. Burnett et al. discuss the use of the conditional error approach to allow adding new arms to a Multi-Arm Multi-Stage (MAMS) trial in progress . Choodari-Oskooei et al. provide methods for calculating the familywise error rate (FWER) when new arms are added to a platform trial . Ventz et al. propose statistical methods for adding new experimental arms after a clinical trial has started enrolling patients . These methods include balanced and outcome-adaptive randomization and have been evaluated using simulation scenarios . Overall, the literature suggests that adding new arms to ongoing trials can be done using various approaches, such as the conditional error approach, and careful consideration of the FWER and trial design is necessary.
Answers from top 5 papers
More filters
| Papers (5) | Insight |
|---|---|
20 Citations | The provided paper does not discuss the experimental treatment of ARMs. |
Open access•Posted Content | The provided paper does not specifically discuss the literature regarding experimental treatment of ARMs. |
Open access•Posted Content 4 Citations | The paper does not discuss any literature regarding the experimental treatment of ARMs. |
3 Citations | The paper does not specifically discuss the literature regarding experimental treatment of ARMs. |
Open access•Posted Content | The provided paper does not specifically mention literature regarding experimental treatment of ARMs. |
Related Questions
What is the purpose of experimental research?5 answersThe purpose of experimental research is to establish a causal relationship between independent variables and dependent variables through empirical observation and control mechanisms. Experimental research is used to address questions of cause and effect, and researchers manipulate the primary independent variable to determine its effect on the outcome. By choosing the levels of explanatory characteristics, associating them with the sample units through a random process, and controlling extraneous characteristics, experimental research reduces confounding effects and avoids bias. Experimental research allows for inferences and can be used for various purposes in health communication research, such as formative research, evaluation research, and testing and refining theories. The appropriate design for experimental research depends on the purpose and objective of the research, as well as the conditions and participants involved.
Write publications about edema in arms post mastectomy?5 answersPost-mastectomy edema in the arms, also known as lymphedema or postmastectomy oedema (PMO), is a common condition following breast cancer treatment. The incidence of lymphedema ranges from 16-40% after axillary lymph node dissection. Even sentinel lymph node biopsy alone can lead to lymphedema in 3.5% of patients. Risk factors for lymphedema include prolonged or high volume seroma, taxane-based chemotherapy, radiotherapy to the axilla, and post-radiation skin necrosis. Complications and intercurrences following breast cancer surgery can also contribute to the development of edema. Imaging techniques such as CT scans can be used to assess the edematous components and detect fibrotic tissue in the affected arm. It is important to provide appropriate nursing follow-up and patient guidance to prevent and manage edema. Understanding the underlying pathophysiological mechanisms of post-mastectomy edema remains an ongoing area of research.
What are the treatments for tennis elbow?5 answersThe treatments for tennis elbow include conservative measures such as rest and activity modification, as well as adjunctive treatments like steroid injections, autologous blood or platelet-rich plasma (PRP) injections, and exercise. Steroid injections may provide short-term relief but do not offer long-term benefit. Percutaneous needle fenestration and surgical management, such as open or arthroscopic release of the affected muscle tendon, may be considered in refractory cases. Other options like Traumeel, hyaluronic acid, botulinum toxin, and polidocanol have been used, but the effectiveness of these treatments is inconsistent. PRP, which can be leukocyte-rich (LR-PRP) or leukocyte-poor (LP-PRP), has gained popularity but conclusive data regarding its efficacy are still pending. Dextrose prolotherapy has shown to be a cost-effective treatment option for tennis elbow, providing long-lasting results compared to steroid injections.
What are the most effective physiotherapy treatments for arm pain?5 answersPhysiotherapy treatments for arm pain have been investigated in several studies. One study found that a physiotherapeutic treatment with manual therapy resulted in significant improvement in shoulder flexion arm mobility compared to a control group. Another study compared different management strategies for distal arm pain and found that advice to remain active while awaiting physiotherapy resulted in better functional outcomes at 26 weeks compared to advice to rest. However, immediate physiotherapy did not provide additional benefit in terms of disability compared to physiotherapy delivered after a waiting period. These findings question the current guidance for the management of distal arm pain. Overall, physiotherapy treatments that include manual therapy and advice to remain active appear to be effective in improving arm mobility and functional outcomes in patients with arm pain.
What are some examples of experimental research?4 answersExperimental research designs have been used in various fields. For example, in the field of music teaching and learning, researchers use experimental designs to test theories and hypotheses about the effects of different teaching methods on student outcomes. In the natural and biological sciences, experiments have been used to verify theories and identify causal relationships. An example is early humans conducting experiments in agriculture to determine the most effective methods for maximizing yields. In the field of leadership research, experimental methods such as vignette studies, laboratory experiments, and field experiments have been used to gain insight into causal relationships and test interventions. Experimental research is also used in the field of Foreign Policy Analysis, particularly for studying microfoundational questions related to public opinion and decision-making.
Is a randomized clinical trial experimental?10 answers