Whereas EC reduced prevalence of infection to 83.3% and 93.3% with doses 1200 and 600 mg kg−1, respectively
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In a study comparing different praziquantel regimens for S. mansoni infection, it was found that a single dose of 40 mg/kg and two divided doses of 60 mg/kg administered 6 hours apart resulted in varying cure rates. The regimen of 60 mg/kg in two divided doses showed a better cure rate of 96% compared to 85% with the 40 mg/kg single dose . Additionally, the study highlighted that the prevalence of infection increased 12 months post-treatment but remained lower than before treatment, indicating ongoing transmission from nearby hyperendemic areas . This suggests that the higher dose regimen of 60 mg/kg in two divided doses may be more effective in reducing the prevalence of S. mansoni infection compared to the lower dose regimen of 40 mg/kg as seen in the study conducted in Beheira Governorate.
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Open access•Journal Article 3 Citations | Not addressed in the paper. |
| The study focused on three monthly doses of 60 mg/kg praziquantel for Schistosoma haematobium, achieving a 96.4% cure rate, contrasting with lower rates for other doses mentioned. | |
| Not addressed in the paper. |
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