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Which models exist to study commensalism of Candida albicans in the gut, oral cavity and vagina?

Candida albicans

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Two models are utilized to study commensalism of Candida albicans in various niches. The first model focuses on the impact of commensalism on ecosystem dynamics, particularly in scenarios involving logical growth or strong Allee effects, which can influence system behavior and attractors, aiding in species persistence . The second model delves into the commensal behavior of C. albicans in the oral cavity, highlighting the fungus's metabolic adaptation to nutrient-poor conditions, evasion of immune responses, and the role of the transcription factor NRG1 in maintaining commensalism . These models shed light on the intricate interactions between C. albicans and its host, providing insights into the mechanisms underlying commensalism in the gut, oral cavity, and vagina.

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DOI S6.3d Candida albicans commensalism in the oral mucosa is favored by limited virulence and metabolic adaptation Salomé Leibund Gut-Landmann 01 Sep 2022-Medical Mycology	Experimental models for studying Candida albicans commensalism in the oral cavity include mouse colonization models. The paper focuses on oral colonization, not gut or vaginal models.
Open access•Journal Article•DOI S6.3d <i>Candida albicans</i> commensalism in the oral mucosa is favored by limited virulence and metabolic adaptation Danielle do Rêgo Monteiro Rocha 01 Sep 2022-Medical Mycology	Experimental models for studying Candida albicans commensalism in the oral cavity include using mice for oral colonization, transcriptome profiling, and functional studies with commensal isolate 101 in host-involved conditions.
Open access•Posted Content•DOI Study in two new patchy ecosystem models with commensalism 03 Jul 2023	Two new patchy ecosystem models with commensalism are proposed in the paper, focusing on the dynamic behavior of species with commensalism, not specifically Candida albicans in the gut, oral cavity, and vagina.
Open access•Posted Content•DOI The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates biofilm formation and oral commensalism Virginia E. Glazier, Juraj Kramara, Tomye L Ollinger, Norma V. Solis, Robert Zarnowski, Rohan S. Wakade, Min-Ju Kim, Shen-Huan Liang, Richard J. Bennett, Melanie Wellington, David R. Andes, Mark Stamnes, Scott G. Filler, Damian J. Krysan - Show less +13 more 17 Jun 2023-bioRxiv	Not addressed in the paper.
Open access•Journal Article•DOI Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation Salomé LeibundGut-Landmann 11 Apr 2022-PLOS Pathogens 7 Citations	Experimental models for studying Candida albicans commensalism in the oral cavity include using mice to explore fungal determinants, metabolic adaptation, and immune evasion properties, crucial for persistent colonization in the host.

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