Why are amino groups soluble in organic solvents?
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Amino groups can be made soluble in organic solvents through various methods. One effective approach highlighted in the literature involves ion-pairing, where enzymes are solubilized in organic solvents by forming nano-complexes with counter-charged surfactant molecules, allowing for homogeneous distribution and improved reaction efficiency . Additionally, the solubility of aminocaproic acid, which contains amino groups, was found to be significantly higher in water compared to other organic solvents, indicating a potential affinity for water-soluble environments . Furthermore, the use of specific solvent systems containing strong acids and tertiary bases with low pK values has been shown to effectively dissolve amino acids and their derivatives, facilitating interactions with acylating reagents and enabling the synthesis of various amino acid derivatives with high yields .
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| Papers (5) | Insight |
|---|---|
8 Citations | Amino groups in amino acids become soluble in organic solvents due to the formation of salts with strong acids like CF3COOH in the presence of a tertiary base with pK ≤ 6. |
6 Citations | Not addressed in the paper. |
4 Citations | Amino groups become soluble in organic solvents due to ion-pairing with surfactants, forming enzyme nano-complexes that enhance solubility and reaction efficiency in non-aqueous biocatalysis. |
Patent 04 Aug 2008 4 Citations | Amino groups are soluble in organic solvents due to the presence of a method and device that efficiently recovers water-soluble organic solvents with amino groups like MEA from water. |
Patent 18 Feb 2010 3 Citations | Amino groups are soluble in organic solvents like MEA due to efficient recovery methods involving cation exchange resin adsorption and elution processes outlined in the paper. |
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