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Why is dengue a global public health issue? 


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Dengue has emerged as a significant global public health issue due to a confluence of factors that have contributed to its widespread transmission and the challenges associated with its management and control. The disease, caused by the dengue virus transmitted primarily through Aedes mosquitoes, has seen a dramatic increase in incidence, with an estimated 400 million infections occurring annually worldwide. This rise is attributed to several key factors, including climate change, which has led to an increase in ambient temperatures and modifications in precipitation cycles, facilitating the expansion of the geographical areas suitable for the vectors. Additionally, rapid and unplanned urbanization, coupled with ineffective vector control methods, has created ideal breeding grounds for Aedes mosquitoes. The severity of the disease, which can escalate to dengue hemorrhagic fever, poses a significant threat to public health, particularly in tropical and subtropical regions where the disease is endemic. Despite the high burden, the lack of effective antiviral therapies and vaccines complicates the management of dengue, leaving vector control measures as the primary strategy for prevention. The global distribution of dengue is further exacerbated by international travel and the movement of infected individuals, contributing to its spread across new regions. Efforts to develop vaccines have seen some progress, with the first licensed dengue vaccine showing serostatus-dependent performance, and other candidates currently undergoing clinical trials. However, challenges in vaccine development, including achieving balanced immunity to all virus serotypes and overcoming interference between attenuated viruses, remain significant hurdles. The socioeconomic impact of dengue, particularly in countries with limited resources, underscores the need for coordinated global public health policies and targeted interventions to combat this disease. The ongoing research and development efforts aimed at understanding dengue pathogenesis and developing effective vaccines are crucial steps toward mitigating the global impact of this infectious disease.

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Dengue is a global public health issue due to climate changes, international travel, urbanization, ineffective vector control, and lack of antiviral drugs and vaccines, affecting over 2.5 billion people worldwide.
Dengue is a global public health issue due to its high prevalence, socioeconomic burden, challenges in control, and impact on limited resources, necessitating coordinated public policies globally for effective management.
Dengue poses a global public health threat due to its widespread transmission by Aedes mosquitoes, increasing frequency of epidemics, substantial economic burden, and lack of specific antiviral therapies.
Dengue is a global public health issue due to its rapid spread, lack of effective antiviral drugs and vaccines, leading to severe cases and high mortality rates worldwide.
Dengue is a global public health issue due to increasing incidence, expanding geographical range of Aedes vectors, and potential epidemic threats in Europe, especially for immunologically naïve populations.

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