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Why would someone want to continuously monitor creatinine?

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Continuous monitoring of creatinine is crucial for various reasons. It allows for real-time tracking of kidney function, aiding in the early detection of kidney issues like kidney failure . Continuous monitoring can provide a comprehensive view of creatinine levels, especially in high-risk groups like diabetic patients, helping in timely intervention and management . Additionally, continuous monitoring of creatinine can be achieved through innovative biosensor technologies, such as quartz resonator-based thermal biosensors, which offer high sensitivity and accuracy without the need for invasive procedures . This non-contact method ensures clear calorimetric data without mass loading effects, making it ideal for continuous monitoring of kidney function based on urinary creatinine excretion . Overall, continuous creatinine monitoring is essential for proactive healthcare management and early detection of kidney-related issues.

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Journal Article•DOI Continuous intra-abdominal pressure monitoring: this is the way to go! Manu L N G Malbrain, I. De Laet, J. J. De Waele - Show less +2 more 01 Mar 2008-International Journal of Clinical Practice 9 Citations	Not addressed in the paper.
Proceedings Article•DOI An automated miniaturized creatinine sensing system Son Vu Hoang Lai, David E. Gaddes, Srinivas Tadigadapa - Show less +2 more 19 Dec 2013	Continuous monitoring of creatinine allows for real-time assessment of kidney function, aiding in early detection of renal issues, adjustment of treatment plans, and timely intervention to prevent further complications.
Open access•Journal Article•DOI Continuous Physiologic Monitoring: False Alarms and Overdiagnosis. Eric R. Coon, H. Gilbert Welch - Show less +1 more 25 Apr 2018-Journal of Hospital Medicine 1 Citations	Not addressed in the paper.
Book Chapter•DOI Continuous monitoring based on bionsensors coupled with artificial intelligence Rocío B. Domínguez Cruz, Gustavo Alonso, Roberto Muñoz, Jean-Louis Marty - Show less +3 more 03 Apr 2014-OmniaScience Monographs 1 Citations	Continuous monitoring of creatinine is essential for quality control in industries like food and beverage, environmental pollution concerns, and multianalyte determination using biosensor arrays coupled with artificial intelligence.
Proceedings Article•DOI A smart creatinine analyser for periodic health monitoring J. Rajesh, Pragathi Prasanna, R. Akshith - Show less +2 more 01 Nov 2018 1 Citations	Continuous creatinine monitoring is crucial for early detection of kidney failure, especially in diabetic patients. The smart creatinine analyzer aids in periodic health monitoring, enabling timely intervention and management.

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Does a molecular imprinting polymer exist for creatinine ?5 answersYes, a molecularly imprinted polymer (MIP) for creatinine detection does exist. Several papers have described the fabrication and characterization of MIPs for creatinine detection. Williams et al. developed nano-molecularly imprinted polymers (nMIPs) using a solid-phase templating method and demonstrated their ability to selectively bind creatinine with a limit of detection of (7.0 ± 0.5) μM. Amininasab et al. synthesized a creatinine molecular imprinted polymer on the surface of goethite nanorods and evaluated its adsorption capacity and selectivity for creatinine. Pitayataratorn et al. fabricated an electrochemical potentiometric biosensor based on the MIP technique for creatinine detection and compared the effectiveness of different functional monomer combinations. Additionally, a study by the authors of Context_5 presented the development of noninvasive electrochemical sensors based on MIPs for the detection of creatinine in urine and saliva. These papers provide evidence for the existence of molecularly imprinted polymers for creatinine detection.

What type of sensors can be used to continuously monitor creatinine ?4 answersCreatinine can be continuously monitored using analyte sensors that are capable of detecting creatinine in vivo. These sensors typically consist of a sensor tail with a creatinine-responsive active area, a permeable membrane that covers the active area, and an oxygen scavenger. Various methods have been developed for the detection of creatinine, including chromatography, spectroscopy, immune sensors, and enzyme-based detections. Nanomaterials such as chemiluminescence, voltametric, amperometric, conductometric, potentiometric, impedimetric, and nano polymer-based sensors have also been used for creatinine detection. Additionally, a SIM card-type pH responsive polymer-modified paper-based biosensing device coupled with a smartphone has been proposed for the determination of urinary creatinine. Electrochemical sensors, both enzymatic and enzymeless, have shown promise for the point-of-care diagnosis of creatinine-related diseases. Permeable outer diffusion control membranes have also been developed for creatinine and creatine sensors.

What are the challenges in developing a urine output monitor that is comfortable for patients to wear?5 answersDeveloping a comfortable urine output monitor for patients faces several challenges. One of the main challenges is sensor design and signal conditioning, which affects the accuracy of signal retrieval. Another challenge is ensuring that the monitor is non-intrusive and does not cause discomfort to the wearer. This involves designing a wearable garment that is lightweight, flexible, and does not restrict movement. Additionally, the monitor should be able to collect urine without causing any harm or discomfort to the patient. This requires careful consideration of the materials used and the design of the collection mechanism. Overall, the development of a comfortable urine output monitor requires addressing these challenges to ensure that patients can wear the monitor without experiencing any discomfort or adverse effects.

How did Continuous Glucose Monitoring invented?3 answersContinuous glucose monitoring (CGM) was invented to provide a more accurate and convenient way to monitor glucose levels in patients with diabetes. The traditional methods of monitoring glucose, such as urine testing and finger sticks, had limitations in terms of accuracy and the ability to detect trends in glucose levels. The development of CGM devices allowed for continuous monitoring of glucose levels, providing real-time data and the ability to detect glycemic excursions at various times throughout the day. CGM devices have evolved over time, with advancements in technology leading to improved accuracy and convenience. These devices typically consist of a body attachment unit that can be easily attached to the body using an applicator, and a wireless communication chip that allows for communication with an external terminal. The user can start the monitoring operation after attaching the body attachment unit, allowing for more accurate glucose monitoring and the ability to adjust the operation start time as needed. The introduction of CGM has significantly improved diabetes management and has become an essential tool for clinicians and patients in achieving glycemic targets.

How did Continuous Glucose Monitoring invent?4 answersContinuous glucose monitoring (CGM) was developed as a way to improve glucose control in patients with diabetes. Traditional methods of monitoring glucose levels, such as urine testing and fingerstick blood glucose measurements, had limitations in terms of accuracy and the ability to detect trends in glucose levels. The development of CGM devices allowed for continuous monitoring of glucose levels, providing more accurate and real-time information about glycemic control. CGM devices use various technologies, including electrochemical sensors and wireless communication chips, to measure glucose levels and transmit the data to external terminals for analysis and interpretation. The use of CGM has been shown to confer significant glycemic benefits for individuals with type 1 and type 2 diabetes, leading to increased adoption of this technology in clinical practice.

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