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Showing papers on "Alveolar hydatid disease published in 1979"


Journal ArticleDOI
02 Mar 1979-JAMA
TL;DR: The clinical, serological, and pathological findings led to the diagnosis of alveolar hydatid disease, and specific identification of Echinococcus multilocularis was achieved by growing mature larvas in voles inoculated intraperitoneally with tissue from the hepatic lesions.
Abstract: A 56-year-old woman from southwestern Minnesota underwent an extended left hepatic lobectomy to remove a large multinodular mass with a necrotic central cavity. The clinical, serological, and pathological findings led to the diagnosis of alveolar hydatid disease, and specific identification of Echinococcus multilocularis was achieved by growing mature larvas in voles inoculated intraperitoneally with tissue from the hepatic lesions. The patient probably acquired her infection some years previously from pet cats or dogs that had become infected by ingesting infected rodents. In North America E multilocularis is enzootic in the northern tundra zone of Alaska and Canada. Since 1964 the cestode has been recognized with increasing frequency in several north-central states, including Minnesota. The parasite may extend its range farther south, since suitable animal hosts occur throughout the United States. ( JAMA 241:904-907, 1979)

51 citations



Journal ArticleDOI
TL;DR: The results indicate an antibody picture which confirms the value of serum-antibodies in the diagnosis of hydatid disease and the indirect haemagglutination test with alveolaris antigen proved to be the most sensitive reaction for antibody demonstration of both echinococci.
Abstract: Serum samples of 107 patients with cystic and 30 with alveolar hydatid disease were tested for antibodies with hydatid fluid and extract from cyst material of E. alveolaris as antigens. Complement-fixation, indirect haemagglutination and an indirect enzyme immune (ELISA) technique were employed. The results indicate an antibody picture which confirms the value of serum-antibodies in the diagnosis of hydatid disease. Diagnostically insufficient antibody formation was present in seven patients with cystic and two with alveolar hydatid disease. The indirect haemagglutination test with alveolaris antigen proved to be the most sensitive reaction for antibody demonstration of both echinococci, while the same antigen in the ELISA technique gave species-specific results in patients with E. alveolaris.

5 citations


Journal ArticleDOI
TL;DR: Differential diagnosis in malignant liver diseases is often impossible, but early venous filling and arteriovenous shunts are not characteristic of multilocular hydatid disease of the liver.
Abstract: From 1973 to 1978 13 cases of cystic hydatid disease and 15 cases of alveolar hydatid disease of the liver were diagnosed by angiography. The main diagnostic features of cystic hydatid disease of the liver are the following: "rim-sign", avascular areas, curved displacement of the arteries and stretching of the intrahepatic arteries. Multilocular hydatid disease of the liver shows tumor-like angiographic signs, such as atypical vascular formations, distensions, vascular irregularities, arterial stenoses as well as hepatosplenomegaly. Differential diagnosis in malignant liver diseases is often impossible, but early venous filling and arteriovenous shunts are not characteristic of multilocular hydatid disease of the liver. Particularly difficult is the interpretation in patients who have had previous surgery.

2 citations