Showing papers on "Antimicrobial peptides published in 1986"
TL;DR: The results indicate that appropriate positioning of cationic and hydrophobic groups in the stable alpha-helical structure of the peptides is important to exhibit antimicrobial activity.
84 citations
TL;DR: Rabbit granulocytes contain six antimicrobial peptides that are structurally homologous to the human neutrophil "defensins" and can act synergistically against potential pathogens.
Abstract: Rabbit granulocytes contain six antimicrobial peptides that are structurally homologous to the human neutrophil "defensins." NP-5, a rabbit defensin, lacks significant activity against Candida albicans. Nevertheless, its addition to submicromolar concentrations of rabbit NP-1, NP-2, or NP-3a potentiates their candidacidal effect. Thus, granulocyte defensins can act synergistically against potential pathogens.
34 citations