Showing papers on "Clear-cell sarcoma published in 1987"

Renal sarcoma and sarcomatoid renal cell carcinoma: ct and angiographic features

Abstract: Computed tomographic (CT) and angiographic findings in 14 patients (eight men, six women, aged 30-72 years) with sarcomatoid renal cell carcinoma (SRCC) and various types of renal sarcoma are described. There were four patients with SRCC; three, leiomyosarcoma; two, liposarcoma; two, fibrosarcoma; and one each of unclassified renal sarcoma, clear cell sarcoma, and malignant fibrous histiocytoma. The most frequent presenting symptom was an abdominal mass or pain. All 14 patients underwent CT, and 11 underwent selective renal angiography. The diagnosis of renal sarcoma should be suspected when CT findings suggest that the tumor arises from the renal capsule or renal sinus and when the tumor is hypovascular or avascular on angiograms. The characteristic negative attenuation values for liposarcomas permit a specific diagnosis. Sarcomas that originate in the renal parenchyma and SRCC cannot be easily differentiated from renal cell carcinoma; however, renal sarcomas do not appear to have a propensity for extens...

“Clear Cell” Atypical Fibroxanthoma

Abstract: An 87-year-old man with extensive solar damage presented with a 2-month history of a dome-shaped, crusted lesion on the dorsum of the left hand. Microscopically, the tumor consisted of fascicles of spindle cells with bizarre nuclei and clear, vacuolated cytoplasm. Histochemical, immunohistochemical, and ultrastruc-tural features supported the diagnosis of atypical fibroxanthoma. There was no evidence of metastatic disease. The lesion was completely excised, and there has been no recurrence in 3 months of observation. This unusual “clear cell” variant of atypical fibroxanthoma must be distinguished from other clear cell tumors, such as metastatic renal cell carcinoma, clear cell eccrine carcinoma, and clear cell sarcoma (malignant melanoma) of soft parts. Although atypical fibroxanthoma is usually cured by complete surgical excision, metastases have been reported.

Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts) with unusual roentgenologic findings. Case report.

Abstract: Clear cell sarcoma of tendons and aponeuroses (malignant melanoma of soft parts) with bone invasion of the proximal tibia occurred in a 15-year-old boy. The tumor arose from the juxtacortical region and invaded the tibia. Bone involvement in this tumor is rare.

[Orbital localization of clear-cell sarcoma of tendons and aponeuroses. Apropos of a case report].

Abstract: Clear cell sarcoma of tendons and aponeuroses actually is a well identified soft tissue tumor. A primary orbital involvement is presented, with an optical and electron microscopic study. The orbital topography of such a tumor seems to be an exceptional opportunity. The histological study showed the typical pattern of this clear cell tumor. Ultrastructurally, there are not absolute specific features to establish the diagnosis, except the finding of intra-cellular melanosomes. Histogenesis has been debated for a long time between a melanotic or a synovial origin. According to present knowledge, this tumor may be attributed to a neural crest origin.

[Soft tissue neoplasms--progress and limits of pathologico-anatomic diagnosis].

Abstract: Current classifications of soft tissue tumors are based principally on the histogenetic type of the tumor thereby abandoning descriptive terms such as spindle cell sarcoma, round cell sarcoma etc. Insight into the histogenesis of a number of soft tissue tumor types has been gained from electron microscopical studies. In addition, these studies provided valuable data to establish certain neoplasms as tumor entities. Thus, the histogenesis of clear cell sarcoma of tendons and aponeuroses has been traced to melanocytes, and it is now universally accepted that biphasic synovial sarcoma consists of epithelial and fibroblastic components. Despite these advances, about 10% of all soft tissue sarcomas remain unclassified when light- and electron microscopy are used in combination. Further improvement in the classification of soft tissue malignancies has been achieved applying immuno-histological techniques. As in other types of malignant tumors mono- and polyclonal antibodies against intermediate filament proteins are especially useful. Other "markers" include protein S-100, neuronspecific enolase (NSE), epithelial membrane antigen (EMA) and panleucocyte antigen (LCA). Regular use of all these markers enabled us to reduce the percentage of unclassified soft tissue sarcomas from 17.6% in the "pre-immune era" to 6.1%.

A case of malignant melanoma of soft parts of the meck

Abstract: We recently experienced a case of malignant melanoma of the soft tissue, which is a rare disease. The patient was a 29-year-old woman who complained of a mass on the right supraclavicular fossa. Wide resection was performed with dissection of neck lymph nodes as the tumor was suspected to be a clear cell sarcoma of tendons and aponeuroses by incisional biopsy. A tumor embolism was noted in the right subclavian vein. In the surgical specimen, melanin pigment was light-microscopically noted and melanosomes were detected electron-microscopically in the tumor cells. The tumor was diagnosed as soft-tissue malignant melanoma, termed clear cell sarcoma of tendons and aponeuroses by Enzinger et al. The patient underwent DVA adjuvant chemotherapy and is currently alive without any recurrent sign after the operation.

Case 3: Type of Sarcoma?

Abstract: A 18-year-old woman was admitted to the hospital because of pain in the left upper leg. X-ray examination revealed an irregular osteolytic defect in the distal femur with extraosseal extension. A differential diagnosis of Ewing sarcoma, osteosarcoma and osteomyelitis was made. An open biopsy was taken, both from the intra- and extraosseal parts of the lesion.