Showing papers on "Glucal published in 2021"
TL;DR: In this article, the authors developed simple and efficient protocols for palladium-catalyzed regioselective α-and β-arylations of structurally diverse vinyl ethers.
Abstract: We developed simple and efficient protocols for palladium-catalyzed regioselective α- and β-arylations of structurally diverse vinyl ethers. Both catalytic methods proceed under relatively mild reactions conditions applying to a broad substrate range including more complex compounds providing arylated glucal or isochromene. Lacking the common requirement of a large reagent excess, the transformations are highly economic and limiting the waste production. Results from computational studies (DFT) provided insight into the key factors determining the pronounced regioselectivities of the investigated reactions.
4 citations
TL;DR: In this paper, a series of 3-Se 1,2-unsaturated glucosides have been synthesized site-specifically from tri-O-acetyl-d -glucal, 3,4-di-Oacetyl l -rhamnal or 2,4,6-tri-Obenzyl- d -glugal with alkyl(aryl) hydroselenides as the nucleophile precursors in good yield.