Showing papers on "Methylglyoxal published in 1969"
56 citations
TL;DR: Synchronisierte menschliche Nieren-T-Zellen zeigen eine Mitoseverzögerung, wenn sie in der G1-, S- oder G2-Phase des Zyklus Methylglyoxal oder Kethoxal ausgesetzt werden.
Abstract: Synchronisierte menschliche Nieren-T-Zellen zeigen eine Mitoseverzogerung, wenn sie in der G1-, S- oder G2-Phase des Zyklus Methylglyoxal oder Kethoxal ausgesetzt werden. Die Mitoseverzogerung wird durch 5mM Cysteamin eliminiert.
32 citations
TL;DR: The 200-fold purification of glyoxaiase I (EC 4.4.1.5) from calf liver is described, and this enzyme exhibits two marked anomalies in its kinetic behavior.
Abstract: The 200-fold purification of glyoxaiase I (EC 4.4.1.5) from calf liver is described. This enzyme exhibits two marked anomalies in its kinetic behavior. There is an initial lag phase of a few seconds, and the plot of velocity versus enzyme concentration is nonlinear, reaching a plateau value. These features are correlated with the kinetics of formation of the hemimercaptal of glutathione and methylglyoxal, suggesting that this adduct is the true substrate of glyoxaiase I.
28 citations
TL;DR: It is suggested that 21-hydroxysteroid dehydrogenase functions to control the level of 21-dehydrosteroids in the placenta formed by other pathways.
11 citations