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Showing papers on "Periocular Region published in 2007"


01 Jan 2007
TL;DR: Treatment of eyelid basal cell carcinoma needs to be individualized, taking into account patient factors, tumor characteristics, and histological subtype, and clinical features.
Abstract: Basal cell carcinoma is the most common malignancy in humans, and it is also the most frequent periocular malignancy. Although a slow-growing tumor, it can lead to significant morbidity in the periocular region as a result of orbital invasion. As clinical presentation can be very variable, biopsy is recommended for all suspicious lesions. Management needs to be individualized, taking into account patient factors, tumor characteristics, and histological subtype. Several treatment modalities have been proposed, but surgical excision with monitoring of excision margins has the highest cure rate. As a certain percentage of tumors will recur regardless of treatment modality, careful patient counseling and/or long-term follow-up is recommended. In this review, we discuss the risk factors, pathology, molecular biology, clinical features, and management of eyelid basal cell carcinoma.

37 citations


Journal ArticleDOI
TL;DR: The aim of this study was to examine the frequency of periocular involvement in CL in the Çukurova region of Turkey, as well as the clinical characteristics, diagnosis and methods of treatment of this disease.
Abstract: Objective Although cutaneous leishmaniasis (CL) occurs mostly in the facial area, periocular involvement accounts for 2–5% of the facial lesions. CL lesions localized in the periocular region can easily be confused with various other diseases. The aim of this study was to examine the frequency of periocular involvement in CL in the Cukurova region of Turkey, as well as the clinical characteristics, diagnosis and methods of treatment of this disease. Methods Between December 1998 and December 2004, patients who were diagnosed with CL were evaluated prospectively with respect to periocular involvement. Results From the 2066 patients evaluated with CL, 2622 lesions were identified. In 59 (2.9%) of these patients, a total of 66 (2.5%) lesions were located in the periocular area. Thirty-two (48.5%) of these lesions were of the papular type, 15 (22.7%) the nodulo-ulcerative type, 10 (15.2%) the plaque type, and nine (13.6%) the nodular type. Dacryocystitis was identified in four patients with periocular involvement. Over the follow-up period, no ocular or periocular deformities or complications developed in these patients. Conclusion Patients suspected of CL should be evaluated and treated early in the course of their disease to prevent any permanent ocular or periocular deformities.

17 citations


Journal ArticleDOI
TL;DR: A systematic analysis of the relevant literature that supports the use of imiquimod cream 5% in the periocular basal cell carcinoma treatment is accomplished.
Abstract: The basal cell carcinoma is the most common neoplasia of the periocular region, being responsible for 90% of the eyelid malignancies. There has been a significant rate of increase of the neoplasia during the last few years. Although of slow growth and rarely enticing metastases, its extension and location offer great therapeutic difficulties when it involves the periocular region.The surgical treatment is the one currently used for the periocular region, however, new therapeutic methods have been proposed. The reparative surgical techniques might jeopardize so much the eyelid function (ocular protection) as well as the region aesthetic balance. Recently a new approach involving a clinical treatment using topics immune response modifier has been tried. Imiquimod cream 5% is the main representative of this new class of medications, it has been widely studied in the recent past and it has shown great effectiveness in the treatment of the basal cell carcinoma.he purpose of this current work is accomplishing a systematic analysis of the relevant literature that supports the use of imiquimod cream 5% in the periocular basal cell carcinoma treatment.

7 citations


Journal ArticleDOI
TL;DR: A thoughtful preoperative evaluation, conscientious patient selection, comprehensive informed consent, adequate training, and a cautious and conservative approach are reinforced to minimize moderate or even severe aesthetic and functional periocular complications.
Abstract: Laser periocular surgery has achieved an increased popularity, particularly since the widespread use of CO(2) and erbium:yttrium aluminum garnet laser and more recently with the development of nonablative laser technology. The main target of these techniques is to treat photoaging changes to obtain a rejuvenated skin. Despite the relatively safety of these procedures on experienced hands, postoperative complications affecting the periocular region, and the eye itself, may follow laser surgery. More common complications include persistent erythema, hyper- and hypopigmentation, and hypertrophic scarring. Viral, bacterial, or fungal skin infections may also jeopardize the postoperative period after periocular laser treatment. Severe burns, transitory or permanent lower lid ectropion, and even corneal injuries or ocular perforation are among the most severe hazards. The majority of these complications are related to the use of ablative technologies. A thoughtful preoperative evaluation, conscientious patient selection, comprehensive informed consent, adequate training, and a cautious and conservative approach are reinforced to minimize moderate or even severe aesthetic and functional periocular complications. Nonablative laser therapies are notably safer; however, their ability to significantly improve photoaged skin characteristics is still limited.

5 citations


Journal ArticleDOI
TL;DR: A systematic approach to reviewing the ocular history, review of systems, and pertinent physical exam will be discussed, important to identify not only underlying ocular conditions but also potentially serious systemic conditions with ocular manifestations that can impact the patient's overall health.
Abstract: Proper preoperative assessment of the eye and periocular region is essential to verify ocular health and vision and to obtain an optimal surgical result. A systematic approach to reviewing the ocular history, review of systems, and pertinent physical exam will be discussed. This is important to identify not only underlying ocular conditions but also potentially serious systemic conditions with ocular manifestations that can impact the patient's overall health. A thorough exam by a qualified provider is needed if there are any management issues regarding the presence of a condition(s) that can impact the surgical outcome.

3 citations


Journal ArticleDOI
TL;DR: The authors present their experience in diagnostic and treatment patients with recurrent cancers infiltrating of ethmoido-orbito-nasal complex, primarily localized in periocular region and infiltrating intraorbital, ethmoidal and nasal tissues.

2 citations


Journal Article
TL;DR: The clinical, imaging, and histopathological features of a periocular region tumor in a middle-aged man are described and a diagnosis of mantle cell lymphoma is made, based on immunohistochemical staining results.
Abstract: The clinical, imaging, and histopathological features of a periocular region tumor in a middle-aged man are described. A diagnosis of mantle cell lymphoma is made, based on immunohistochemical staining results.

1 citations