Showing papers on "Vaccine trial published in 1978"
TL;DR: In a controlled clinical trial of a polyvalent pseudomonas vaccine in burned patients infected with Pseudomonas aeruginosa all 18 vaccinated patients survived, whereas 8 of 20 unvaccinated patients died.
38 citations
Journal Article•
TL;DR: Pertussis agglutinating antibody determinations showed an equally satisfactory response after 2 and 3 DPT vaccine doses, and a schedule of child immunization requiring a minimum number of contacts with the children was introduced with the aim of evaluating its effectiveness in protecting children from clinical pertussis.
Abstract: In the course of 2 years of surveillance of whooping cough by fortnightly home visits among a population of 24000 in a rural area of Kenya 918 cases were observed with a peak of 218 in December 1974-January 1975 The attack rate was highest (158%) during the 1st year of life; for those ages 0-6 it was 128% 90% of the cases occurred in children age 6 or younger The median age was 35 years the age range 1 month-13 years Girls were significantly more affected than boys The overall case fatality rate was 13% but among infants it was 25 times higher In order to contribute to the improvement of immunization coverage in countries where health resources are limited a schedule of child immunization requiring a minimum number of contacts with the children was introduced into the study area with the aim of evaluating its effectiveness in protecting children from clinical pertussis In this trial the effect of 2 and 3 diphtheria-pertussis-tetanus (DPT) vaccine doses was compared Pertussis agglutinating antibody determinations showed an equally satisfactory response after 2 and 3 DPT vaccine doses (authors) (summary in FRE)
31 citations