A
A. M. Guriev
Researcher at Siberian State Medical University
Publications - 7
Citations - 56
A. M. Guriev is an academic researcher from Siberian State Medical University. The author has contributed to research in topics: Chemistry & Acorus calamus. The author has an hindex of 2, co-authored 5 publications receiving 46 citations.
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Journal ArticleDOI
Water-soluble polysaccharide obtained from Acorus calamus L. classically activates macrophages and stimulates Th1 response.
N. V. Belska,A. M. Guriev,M. G. Danilets,E. S. Trophimova,Evgenya Uchasova,A. A. Ligatcheva,M. V. Belousov,V. I. Agaphonov,V.G. Golovchenko,Mekhman S. Yusubov,Y. P. Belsky +10 more
TL;DR: The results suggest that the pectic polysaccharide from A. calamus L. represents a promising immunomodulating agent that stimulates M1-polarized macrophages and promotes Th1-oriented adaptive immune response.
Journal ArticleDOI
Signaling events during macrophage activation with Betula pendula roth pectic polysaccharides.
A. A. Ligacheva,M. G. Danilets,E. S. Trofimova,Y. P. Belsky,N. V. Belska,G. N. Zyuz’kov,V. V. Zhdanov,A. N. Ivanova,A. M. Guriev,M. V. Belousov,Mekhman S. Yusubov,A. M. Dygai +11 more
TL;DR: The results indicate that Betula pendula polysaccharides are promising substances for creation of immunomodulating drugs.
Journal ArticleDOI
Hypolipidemic activity of the polysaccharide L-rhamnopyranosyl-6-O-methyl-galacturonan in combined administration with HMG-CoA reductase and cholesterol absorption inhibitors
E. E. Buyko,V. V. Ivanov,O. A. Kaidash,O. Yu. Rybalkina,E. A. Kiseleva,S. V. Krivoshchekov,T. L. Kiseleva,A. M. Guriev,M. V. Belousov +8 more
TL;DR: A promising compound is L-rhamnopyranosyl-6-O -methyl-galacturonan (L-RAG), a polysaccharide obtained from the birch leaves (Betula pendula L.). as discussed by the authors evaluated the lipidlowering activity of L-RAG administered in combination with the HMG-CoA reductase inhibitor rosuvastatin or the cholesterol absorption inhibitor ezetimibe.
Journal ArticleDOI
Effects of Water-Soluble Polysaccharides with Different Chemical Structure, Isolated from Acorus calamus L. and Trifolium pratense L., on Nitric Oxide Production: A Screening Study.
A. A. Ligacheva,M. G. Danilets,E. S. Trofimova,E. Yu. Sherstoboev,V. V. Zhdanov,A. M. Guriev,M. V. Belousov,Mekhman S. Yusubov,A. P. Korzh,S. V. Krivoshchekov,A. M. Dygai +10 more
TL;DR: Rhamnogalactouronans from clover PS63-3 in all concentrations and from PS62-5 in a concentration of 100 μg/ml exhibited the highest activity, comparable to the NO-stimulatory activity of the reference LPS, while polysaccharide PS62
Journal ArticleDOI
Effects of Plant Water-Soluble Polysaccharides on the Production of Immunoglobulins E and G1 by Lymphocytes of Mice Sensitized with Ovalbumin
M. G. Danilets,N. V. Belska,Y. P. Belsky,Evgenya Uchasova,E. S. Trophimova,A. A. Ligatcheva,A. M. Guriev,M. V. Belousov,R. R. Ahmedganov,M. S. Usubov,V. I. Agaphonov +10 more
TL;DR: Water-soluble plant polysaccharides isolated from pharmacopoeic raw material reduced animal mortality after induction of anaphylactic shock and production of IgE and IgG1 by lymphocytes from mice immunized with ovalbumin and can be regarded as promising agents for the treatment of Ig E-dependent diseases.