Ammonia chemical ionization mass spectrometry

A survey of side reactions such as oxidation, hydrogenation, reductive removal of substituents and radical processes is presented, and the implications for mass spectroscopic analysis are pointed out.

Reactions between substrate molecules and chemical ionization reagent gases prior to ionization

Reduction of azides under conditions of desorption-chemical ionization or fast-atom-bombardment mass-spectrometry.

The mechanism of double bond reduction occurring in certain conjugated ketones, nitriles, acids and esters under chemical ionization conditions has been studied. The results indicate that the hydrogen radicals present in the chemically ionized plasma are responsible for the reduction of the double bond. This is further supported by experiments with radical traps.

A. Mahender Reddy

Papers

Reduction of olefinic bond under ammonia chemical ionization