A
A V Potekhina
Researcher at Kirov Military Medical Academy
Publications - 28
Citations - 188
A V Potekhina is an academic researcher from Kirov Military Medical Academy. The author has contributed to research in topics: Coronary atherosclerosis & Coronary artery disease. The author has an hindex of 6, co-authored 23 publications receiving 148 citations.
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Journal ArticleDOI
Treg/Th17 balance in stable CAD patients with different stages of coronary atherosclerosis
A V Potekhina,E A Pylaeva,S I Provatorov,Natalya Ruleva,V P Masenko,E.A. Noeva,T. L. Krasnikova,Tatiana I. Arefieva +7 more
TL;DR: The balance of circulating Treg and Th17 in stable angina patients with different stages of coronary atherosclerosis is investigated to assume that the imbalance in pro- and anti-inflammatory/atherogenic lymphocyte subpopulations is associated with Atherosclerosis progression.
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Synthetic peptide fragment (65-76) of monocyte chemotactic protein-1 (MCP-1) inhibits MCP-1 binding to heparin and possesses anti-inflammatory activity in stable angina patients after coronary stenting.
Tatiana I. Arefieva,T. L. Krasnikova,A V Potekhina,N. U. Ruleva,Petr I. Nikitin,T. I. Ksenevich,B. G. Gorshkov,Maria Sidorova,Zh. D. Bespalova,N. B. Kukhtina,S I Provatorov,E.A. Noeva,E. I. Chazov +12 more
TL;DR: Ingramon treatment was accompanied by less pronounced elevation of hsCRP and fibrinogen levels and decreased MCP-1 concentration in plasma in patients after coronary stenting, and the anti-inflammatory activity of the peptide may be mediated by an impaired chemokine interaction with glycosaminoglycans.
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Immunotropic Effects and Proposed Mechanism of Action for 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors (Statins).
TL;DR: The data of statin effects on immune cells (e.g., monocytes and T cells) involved in the development of atherosclerosis and other chronic inflammatory diseases are analyzed.
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The Molecular and Cellular Mechanisms Associated with a Microvascular Inflammation in the Pathogenesis of Heart Failure with Preserved Ejection Fraction.
TL;DR: This review summarizes current concepts about a microvascular inflammation in hypertrophied myocardium and provides a translational perspective of the anti-inflammatory and immunomodulatory approaches in HFpEF.
Journal ArticleDOI
[Lipoprotein(a), its autoantibodies, and circulating T lymphocyte subpopulations as independent risk factors for coronary artery atherosclerosis].
O I Afanasievа,E A Pylaeva,E.A. Klesareva,A V Potekhina,S I Provatorov,M.I. Afanasieva,Krasnikova Tl,V P Masenko,Tatiana I. Arefieva,Sergei N. Pokrovsky +9 more
TL;DR: The slightly elevated Lp(a) concentration along with changes in the level of T lymphocyte subpopulations was first shown to significantly potentiate the risk of progressive and multiple CA lesion in the examinees.