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A. Wesley Burks
Researcher at University of North Carolina at Chapel Hill
Publications - 305
Citations - 31163
A. Wesley Burks is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Peanut allergy & Food allergy. The author has an hindex of 82, co-authored 288 publications receiving 27987 citations. Previous affiliations of A. Wesley Burks include Boston Children's Hospital & University of Arkansas at Little Rock.
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Special articleGuidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report
Joshua A. Boyce,Amal Assa'ad,A. Wesley Burks,Stacie M. Jones,Hugh A. Sampson,Robert A. Wood,Marshall Plaut,Susan F. Cooper,Matthew J. Fenton,S. Hasan Arshad,Sami L. Bahna,Lisa A. Beck,Carol Byrd-Bredbenner,Carlos A. Camargo,Lawrence F. Eichenfield,Glenn T. Furuta,Jon M. Hanifin,Carol Jones,Julie M. Schwaninger +18 more
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Modification of peanut allergen Ara h 3: effects on IgE binding and T cell stimulation.
Pat Rabjohn,C. Michael West,Cathie Connaughton,Hugh A. Sampson,Ricki M. Helm,A. Wesley Burks,Gary A. Bannon +6 more
TL;DR: The engineered hypoallergenic Ara h 3 variant displays two characteristics essential for recombinant allergen immunotherapy; it has a reduced binding capacity for serum IgE from peanut-hypersensitive patients and it can stimulate T-cell proliferation and activation.
Journal ArticleDOI
Food allergies: prevalence, molecular characterization, and treatment/prevention strategies.
Laurie A. Lee,A. Wesley Burks +1 more
TL;DR: The diagnosis of food allergy requires that the patient and caregivers examine all foods for the presence of potential allergens in order to prevent inadvertent ingestion and further reactions.
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Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy.
Scott H. Sicherer,Robert A. Wood,Donald Stablein,A. Wesley Burks,Andrew H. Liu,Stacie M. Jones,David Fleischer,Donald Y.M. Leung,Alexander Grishin,Lloyd Mayer,Wayne G. Shreffler,Robert Lindblad,Hugh A. Sampson +12 more
TL;DR: In this article, the basic mechanisms responsible for food allergy and identify biomarkers, such as skin prick test (SPT) responses, food-specific IgE levels, and mononuclear cell responses, in a cohort of infants with likely milk/egg allergy at increased risk of peanut allergy were explored.
Journal ArticleDOI
Single-cell profiling of peanut-responsive T cells in patients with peanut allergy reveals heterogeneous effector TH2 subsets
David Y. Chiang,Xintong Chen,Stacie M. Jones,Robert A. Wood,Scott H. Sicherer,A. Wesley Burks,Donald Y.M. Leung,Charuta Agashe,Alexander Grishin,Peter Dawson,Wendy F. Davidson,Leah C. Newman,Robert Sebra,Miriam Merad,Hugh A. Sampson,Bojan Losic,M. Cecilia Berin +16 more
TL;DR: The results demonstrate the presence of highly differentiated TH2 cells producing TH2‐associated cytokines with functions beyond IgE class‐switching in patients with PA, and a multifunctional TH2 response was more evident than a Treg cell deficit among peanut‐responsive T cells.