D
Donald Y.M. Leung
Researcher at National Jewish Health
Publications - 669
Citations - 55374
Donald Y.M. Leung is an academic researcher from National Jewish Health. The author has contributed to research in topics: Atopic dermatitis & Allergy. The author has an hindex of 121, co-authored 614 publications receiving 50873 citations. Previous affiliations of Donald Y.M. Leung include Harvard University & Anschutz Medical Campus.
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Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis
Peck Y. Ong,Takaaki Ohtake,Corinne Brandt,Ian Strickland,Mark Boguniewicz,Tomas Ganz,Richard L. Gallo,Donald Y.M. Leung +7 more
TL;DR: A deficiency in the expression of antimicrobial peptides may account for the susceptibility of patients with atopic dermatitis to skin infection with S. aureus.
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New insights into atopic dermatitis
TL;DR: This review summarizes recent progress in the understanding of the pathophysiology of atopic dermatitis and the implications for new management strategies.
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Filaggrin Mutations Associated with Skin and Allergic Diseases
TL;DR: The biology of this molecule and the role of mutations in its altered function offer new insights into a range of conditions not previously thought to be related to one another.
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Atopic Dermatitis: A Disease of Altered Skin Barrier and Immune Dysregulation
TL;DR: New insights into the genetics and pathophysiology of AD point to an important role of structural abnormalities in the epidermis as well as immune dysregulation not only for this skin disease but also for the development of asthma and allergies.
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Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids.
Sally E. Wenzel,Stanley J. Szefler,Donald Y.M. Leung,Steven I. Sloan,Michael D. Rex,Richard J. Martin +5 more
TL;DR: Investigating the presence and type of airway inflammation in patients with severe asthma suggests that inflammation remains in severe symptomatic asthmatics despite treatment with high dose glucocorticoids, which may be due to the severity of disease, glucOCorticoid treatment, or other as yet undefined factors.