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A. Wesley Burks
Researcher at University of North Carolina at Chapel Hill
Publications - 305
Citations - 31163
A. Wesley Burks is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Peanut allergy & Food allergy. The author has an hindex of 82, co-authored 288 publications receiving 27987 citations. Previous affiliations of A. Wesley Burks include Boston Children's Hospital & University of Arkansas at Little Rock.
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Journal ArticleDOI
Long-term sublingual immunotherapy for peanut allergy in children: Clinical and immunologic evidence of desensitization.
TL;DR: Extended-therapy peanut SLIT provided clinically meaningful desensitization in the majority of children with peanut allergy that was balanced with ease of administration and a favorable safety profile.
Journal ArticleDOI
Phenotypic Characterization of Eosinophilic Esophagitis in a Large Multicenter Patient Population from the Consortium for Food Allergy Research.
Mirna Chehade,Stacie M. Jones,Robbie D. Pesek,A. Wesley Burks,Brian P. Vickery,Robert A. Wood,Donald Y.M. Leung,Glenn T. Furuta,David Fleischer,Alice K. Henning,Peter Dawson,Robert Lindblad,Scott H. Sicherer,J. Pablo Abonia,Joseph D. Sherrill,Hugh A. Sampson,Marc E. Rothenberg +16 more
TL;DR: Gastrointestinal eosinophilia is present in approximately 10% of patients with EoE; the symptom-diagnosis time gap is influenced by age, race, food allergy, and atopic dermatitis; symptoms vary with race; concurrent infectious/immunologic disorders and mental health disorders are common; and the level of esophageal eOSinophils is comparable in patients with and without fibrostenotic features.
Journal ArticleDOI
Clinical Characteristics of Peanut-Allergic Children: Recent Changes
Todd D. Green,Virginia S. LaBelle,Pamela H. Steele,Edwin H. Kim,Laurie A. Lee,Vaishali S. Mankad,Larry W. Williams,Kevin J. Anstrom,A. Wesley Burks +8 more
TL;DR: In the past decade, the ages of first peanut exposure and reaction have declined among peanut-allergic children seen in a referral clinic, and sesame seeds should perhaps be considered one of the major food allergens.
Journal ArticleDOI
Anaphylaxis: a history with emphasis on food allergy.
S. Boden,A. Wesley Burks +1 more
TL;DR: Treatment with intramuscular epinephrine continues to be the recommended first‐line therapy, although studies indicate that education of both the patients and the medical community is needed.
Journal ArticleDOI
Mast cell desensitization inhibits calcium flux and aberrantly remodels actin
W.X. Gladys Ang,Alison Church,Mike Kulis,Hae Woong Choi,A. Wesley Burks,Soman N. Abraham,Soman N. Abraham +6 more
TL;DR: It is found that displacement of the actin cytoskeleton and its continued association with FcεRI impede the capacity of desensitized MCs to evoke the calcium response that is essential for MC degranulation.