A
Aarfa Queen
Researcher at Jamia Millia Islamia
Publications - 20
Citations - 654
Aarfa Queen is an academic researcher from Jamia Millia Islamia. The author has contributed to research in topics: Kinase & Cell growth. The author has an hindex of 11, co-authored 18 publications receiving 371 citations.
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Journal ArticleDOI
Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition
Saleha Anwar,Anas Shamsi,Mohd Shahbaaz,Mohd Shahbaaz,Aarfa Queen,Parvez Khan,Gulam Mustafa Hasan,Asimul Islam,Mohamed F. Alajmi,Afzal Hussain,Faizan Ahmad,Md. Imtaiyaz Hassan +11 more
TL;DR: The study provides a rationale for the therapeutic evaluation of RA and RA-based inhibitors in MARK4 associated cancers and other diseases.
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Elucidation of dietary polyphenolics as potential inhibitor of microtubule affinity regulating kinase 4: in silico and in vitro studies.
Parvez Khan,Shafikur Rahman,Aarfa Queen,Saaliqa Manzoor,Farha Naz,Gulam Mustafa Hasan,Suaib Luqman,Jihoe Kim,Asimul Islam,Faizan Ahmad,Md. Imtaiyaz Hassan +10 more
TL;DR: Rutin and vanillin may be considered as potential inhibitors for MARK4 and further exploited to design novel therapeutic molecules against MARK4 associated diseases.
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Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy
Saleha Anwar,Taj Mohammad,Anas Shamsi,Aarfa Queen,Shahnaz Parveen,Shahnaz Parveen,Suaib Luqman,Suaib Luqman,Gulam Mustafa Hasan,Khalid A. Alamry,Naved Azum,Abdullah M. Asiri,Imtaiyaz Hassan +12 more
TL;DR: The findings provide the basis for the therapeutic implication of hordenine and its derivatives in lung cancer and PDK3-related diseases after required in vivo validation.
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Identification of α-Mangostin as a Potential Inhibitor of Microtubule Affinity Regulating Kinase 4
Parvez Khan,Aarfa Queen,Taj Mohammad,Smita,Nashrah Sharif Khan,Zubair Bin Hafeez,Md. Imtaiyaz Hassan,Sher Ali +7 more
TL;DR: ructure-based docking and 100 ns molecular dynamics simulation revealed that the binding of α-mangostin stabilizes the MARK4 structure, and implicates MARK4 as a new target ofα-m Mangostin, adding an additional lead molecule to the anticancer repertoire.
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Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis
Babita Aneja,Nashrah Sharif Khan,Parvez Khan,Aarfa Queen,Afzal Hussain,Md. Tabish Rehman,Mohamed F. Alajmi,Hesham R. El-Seedi,Sher Ali,Md. Imtaiyaz Hassan,Mohammad Abid +10 more
TL;DR: 9g seems to possess an effective inhibitory potential towards MARK4 adding an additional repertoire to anticancer therapeutics.