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Aaron M. Mohs
Researcher at University of Nebraska Medical Center
Publications - 72
Citations - 3678
Aaron M. Mohs is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 25, co-authored 67 publications receiving 3149 citations. Previous affiliations of Aaron M. Mohs include Emory University & Georgia Institute of Technology.
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Bioconjugated quantum dots for in vivo molecular and cellular imaging
TL;DR: The synthesis and development of state-of-the-art QD probes and their use for molecular and cellular imaging are discussed and key issues for in vivo imaging and therapy, such as nanoparticle biodistribution, pharmacokinetics, and toxicology are examined.
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Tuning the optical and electronic properties of colloidal nanocrystals by lattice strain
TL;DR: The epitaxial deposition of a compressive shell onto a soft nanocrystalline core to form a lattice-mismatched quantum dot can dramatically change the conduction and valence band energies of both the core and the shell.
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Hand-held Spectroscopic Device for In Vivo and Intraoperative Tumor Detection: Contrast Enhancement, Detection Sensitivity, and Tissue Penetration
Aaron M. Mohs,Michael C. Mancini,Sunil Singhal,James M. Provenzale,James M. Provenzale,Brian Leyland-Jones,May D. Wang,Shuming Nie +7 more
TL;DR: In vivo studies using mice bearing bioluminescent 4T1 breast tumors further demonstrate that the tumor borders can be precisely detected preoperatively and intraoperatively, and that the contrast signals are strongly correlated with tumor biolUMinescence.
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Indocyanine Green-Loaded Nanoparticles for Image-Guided Tumor Surgery
Tanner K. Hill,Asem I. Abdulahad,Sneha S. Kelkar,Frank C. Marini,Timothy Edward Long,James M. Provenzale,Aaron M. Mohs +6 more
TL;DR: A series of hyaluronic acid-derived nanoparticles that entrap the near-infrared dye indocyanine green, termed NanoICG, for improved delivery of the dye to tumors and was found to be nontoxic at physiologically relevant concentrations and exposure was not found to inhibit cell growth.
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Impact of structurally modifying hyaluronic acid on CD44 interaction
Deep S. Bhattacharya,Denis Svechkarev,Joshua J. Souchek,Tanner K. Hill,Margaret A. Taylor,Amarnath Natarajan,Amarnath Natarajan,Aaron M. Mohs +7 more
TL;DR: These studies indicated that while both deacetylation and sulfation of HA individually decrease CD44 interaction, both chemical modifications are required to minimize interaction with CD44+ cells.