A
Abbas Khan
Researcher at Shanghai Jiao Tong University
Publications - 78
Citations - 2062
Abbas Khan is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Epitope & Reverse vaccinology. The author has an hindex of 16, co-authored 78 publications receiving 938 citations. Previous affiliations of Abbas Khan include Korea University & Chinese Ministry of Education.
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Higher infectivity of the SARS-CoV-2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data.
Abbas Khan,Tauqir Zia,Muhammad Suleman,Taimoor Khan,Syed Shujait Ali,Aamir Ali Abbasi,Anwar Mohammad,Dong-Qing Wei +7 more
TL;DR: In this article, a structural and biophysical analysis of the Spike glycoprotein of SARS-CoV-2 new variants has been carried out to understand the binding and structural dynamics of the new mutations in the RBD domain of Spike protein.
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Marine natural compounds as potents inhibitors against the main protease of SARS-CoV-2-a molecular dynamic study.
Muhammad Tahir Khan,Arif Ali,Qiankun Wang,Muhammad Irfan,Abbas Khan,Muhammad Zeb,Yu Juan Zhang,Sathishkumar Chinnasamy,Dong-Qing Wei +8 more
TL;DR: Marine natural compounds may be used as a potential inhibitor against SARS-CoV-2 for better management of COVID-19, a single-stranded RNA virus responsible for severe acute respiratory disease.
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Virtual screening-driven drug discovery of SARS-CoV2 enzyme inhibitors targeting viral attachment, replication, post-translational modification and host immunity evasion infection mechanisms.
Mark Tristan J. Quimque,Mark Tristan J. Quimque,Kin Israel Notarte,Rey Arturo T. Fernandez,Mark Andrew O. Mendoza,Rhenz Alfred D Liman,Justin Allen K. Lim,Luis Agustin E. Pilapil,Jehiel Karsten H. Ong,Adriel M. Pastrana,Abbas Khan,Dong-Qing Wei,Allan Patrick G. Macabeo +12 more
TL;DR: Nine antiviral secondary metabolites from fungi were docked onto five SARS-CoV2 enzymes involved in viral attachment, replication, post-translational modification, and host immunity evasion infection mechanisms followed by molecular dynamics simulation and in silico ADMET prediction.
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Immunoinformatics approaches to explore Helicobacter Pylori proteome (Virulence Factors) to design B and T cell multi-epitope subunit vaccine
Mazhar Khan,Shahzeb Khan,Asim Ali,Hameed Akbar,Abrar Mohammad Sayaf,Abbas Khan,Abbas Khan,Dong-Qing Wei +7 more
TL;DR: These analyses indicate that the suggested vaccine may produce particular immune responses against H. pylori, but laboratory validation is needed to verify the safety and immunogenicity status of the proposed vaccine design.
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Phylogenetic Analysis and Structural Perspectives of RNA-Dependent RNA-Polymerase Inhibition from SARs-CoV-2 with Natural Products.
Abbas Khan,Mazhar Khan,Shoaib Saleem,Zainib Babar,Arif Ali,Abdul Aziz Khan,Zain Sardar,Fahad Hamayun,Syed Shujait Ali,Dong-Qing Wei +9 more
TL;DR: This study paved a way for designing novel drugs by decoding the architecture of an important enzyme and its inhibition with compounds from natural resources by using computational virtual screening and molecular docking approaches.