A
Abbas Khan
Researcher at Shanghai Jiao Tong University
Publications - 78
Citations - 2062
Abbas Khan is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Epitope & Reverse vaccinology. The author has an hindex of 16, co-authored 78 publications receiving 938 citations. Previous affiliations of Abbas Khan include Korea University & Chinese Ministry of Education.
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Journal ArticleDOI
Network Pharmacology: Exploring the Resources and Methodologies.
TL;DR: Recent advances in the development of methodologies for the identification of drug target interaction and its application in the poly-pharmacology profile of the drug are overviewed.
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Structural and free energy landscape of novel mutations in ribosomal protein S1 (rpsA) associated with pyrazinamide resistance.
Muhammad Tahir Khan,Abbas Khan,Ashfaq Ur Rehman,Yanjie Wang,Khalid Pervaiz Akhtar,Shaukat Iqbal Malik,Dong-Qing Wei +6 more
TL;DR: Investigating the molecular mechanism of resistance behind mutations, D342N, D343N, A344P, and I351F, present in the MtRpsACTD through molecular dynamic simulations (MD) may provide a better insight into the resistance mechanism to achieve the global TB control targets.
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Identification of target gene and prognostic evaluation for lung adenocarcinoma using gene expression meta-analysis, network analysis and neural network algorithms.
Gurudeeban Selvaraj,Satyavani Kaliamurthi,Aman Chandra Kaushik,Abbas Khan,Yong-Kai Wei,William C. Cho,Keren Gu,Dong-Qing Wei,Dong-Qing Wei +8 more
TL;DR: This study has identified novel candidate biomarkers, pathways, transcription factors (TFs), and kinases associated with NSCLC prognosis, as well as drug candidates, which may assist treatment strategy forNSCLC patients.
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Preliminary Structural Data Revealed That the SARS-CoV-2 B.1.617 Variant's RBD Binds to ACE2 Receptor Stronger Than the Wild Type to Enhance the Infectivity.
Abbas Khan,Dong-Qing Wei,Kafila Kousar,Jehad Abubaker,Sajjad Ahmad,Javaid Ali,Fahd Al-Mulla,Syed Shujait Ali,N. Nizam-Uddin,Abrar Mohammad Sayaf,Anwar Mohammad +10 more
TL;DR: In this paper, structural and biomolecular simulation techniques were used to explore the impact of specific mutations (L452R-E484Q) in the B.1.617 variant on the binding of RBD to the host receptor ACE2.
Journal ArticleDOI
An Integrated Systems Biology and Network-Based Approaches to Identify Novel Biomarkers in Breast Cancer Cell Lines Using Gene Expression Data.
Abbas Khan,Zainab Rehman,Huma Farooque Hashmi,Abdul Aziz Khan,Muhammad Junaid,Abrar Mohammad Sayaf,Syed Shujait Ali,Fakhrul Hassan,Wang Heng,Dong-Qing Wei,Dong-Qing Wei +10 more
TL;DR: Network-based gene expression profiling is a suggested tool for discovering drug targets by incorporating various factors such as disease states, intensities based on gene expression as well as protein–protein interactions into this study.