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Ada C. Felix-Ortiz
Researcher at Picower Institute for Learning and Memory
Publications - 15
Citations - 2346
Ada C. Felix-Ortiz is an academic researcher from Picower Institute for Learning and Memory. The author has contributed to research in topics: Amygdala & Prefrontal cortex. The author has an hindex of 11, co-authored 13 publications receiving 1840 citations. Previous affiliations of Ada C. Felix-Ortiz include Northeastern University.
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Journal ArticleDOI
A Circuit Mechanism for Differentiating Positive and Negative Associations
Praneeth Namburi,Anna Beyeler,Suzuko Yorozu,Gwendolyn G. Calhoon,Sarah A. Halbert,Romy Wichmann,Stephanie S. Holden,Kim L. Mertens,Melodi Anahtar,Ada C. Felix-Ortiz,Ian R. Wickersham,Jesse M. Gray,Kay M. Tye +12 more
TL;DR: This work shows that BLA neurons projecting to the nucleus accumbens (NAc projectors) or the centromedial amygdala (CeM projector) undergo opposing synaptic changes following fear or reward conditioning, and provides a mechanistic explanation for the representation of positive and negative associations within the amygdala.
Journal ArticleDOI
BLA to vHPC inputs modulate anxiety-related behaviors.
Ada C. Felix-Ortiz,Anna Beyeler,Changwoo Seo,Christopher A. Leppla,Craig P. Wildes,Kay M. Tye +5 more
TL;DR: A role for BLA-vHPC synapses in bidirectionally controlling anxiety-related behaviors in an immediate, yet reversible, manner is established and a model for the local circuit mechanism of BLA inputs in the vHPC is modeled.
Journal ArticleDOI
Amygdala Inputs to the Ventral Hippocampus Bidirectionally Modulate Social Behavior
Ada C. Felix-Ortiz,Kay M. Tye +1 more
TL;DR: BLA inputs to the vHPC are capable of modulating social behaviors in a bidirectional manner, indicating that the amygdala has long been linked to social interaction and is capable of connecting to downstream regions in noncompetitive social behavior.
Journal ArticleDOI
Bidirectional modulation of anxiety-related and social behaviors by amygdala projections to the medial prefrontal cortex
Ada C. Felix-Ortiz,Anthony Burgos-Robles,Neha D. Bhagat,Neha D. Bhagat,Christopher A. Leppla,Kay M. Tye +5 more
TL;DR: A causal relationship between activity in the BLA-mPFC pathway and the bidirectional modulation of anxiety-related and social behaviors is established.
Bidirectional modulation of anxiety-related and social behaviors by amygdala projections to the medial prefrontal cortex
Ada C. Felix-Ortiz,Anthony Burgos-Robles,Neha D. Bhagat,Neha D. Bhagat,Christopher A. Leppla,Kay M. Tye +5 more
TL;DR: In this article, the authors proposed a method to use the National Research Service (NRS) Institutional Research Training Grant 5T32GM007484-38 (NRTG) to train a classifier.