Adam C. Rothenberg

TL;DR: The routine use of implant sonicate cultures in arthroplasty revisions improves the diagnostic sensitivity for detecting the presence of bacteria in both clinical and occult infections.

TL;DR: Reducing the cost of treating musculoskeletal infection depends on incentivizing innovations in infection prevention, and without the ability to risk-stratify patient outcomes based on patient comorbidities, healthcare organizations are disincentivized to care for moderate- to high-risk patients.

TL;DR: A significant correlation of aldehyde dehydrogenase (ALDH) activity and the presence/absence of distant metastases in ten consecutive cases of human bone sarcomas is described.

TL;DR: It is observed that Notch-activating factors reside in the exosomes of osteosarcoma cells, which activate Notch signaling in MDSCs and subsequently repress myogenesis, which may play an important role in mediating the skeletal muscle atrophy seen in cancer cachexia.

TL;DR: The findings clearly demonstrate the antimicrobial activity of adult ASCs against S. aureus and implicate a key regulatory role for vitamin D.