Adam J. Bogdanove

TL;DR: Targeting is complicated to an extent by a general requirement for thymine to precede the DNA target, a requirement of TALENs to bind paired opposing sites separated by a defined range of distances, differential contributions of different repeat types to overall affinity, and a polarity to mismatch tolerance.

TL;DR: This article reviews the protein-protein interactions described in pathogen recognition by plants, and provides examples of how rapid future progress will hinge on the adoption of new and developing technologies.

TL;DR: Construction and validation of a two-genome microarray for the two pathovars of X. oryzae revealed that using representative strains, a greater number of Xoo genes than Xoc genes are differentially expressed in XOM2 relative to PSB, and that these include hrp genes and other genes important in interactions with rice.

TL;DR: This giant sequoia reference genome sequence represents the first genome sequenced in the Cupressaceae family, and lays a foundation for using genomic tools to aid in giant Sequoiadendron giganteum conservation and management.

TL;DR: Generating TAL effector scaffolds with high activity that robustly accommodate sites without a T at position 0 may require larger scale re-engineering.