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Adam Mauskapf
Researcher at Harvard University
Publications - 31
Citations - 552
Adam Mauskapf is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Intravascular ultrasound. The author has an hindex of 10, co-authored 22 publications receiving 430 citations. Previous affiliations of Adam Mauskapf include Technische Universität München.
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Journal ArticleDOI
Two-Dimensional Intravascular Near-Infrared Fluorescence Molecular Imaging of Inflammation in Atherosclerosis and Stent-Induced Vascular Injury
Farouc A. Jaffer,Marcella A. Calfon,Amir Rosenthal,Amir Rosenthal,Georgios Mallas,Georgios Mallas,R. Nika Razansky,Adam Mauskapf,Ralph Weissleder,Peter Libby,Vasilis Ntziachristos +10 more
TL;DR: A new 2D intravascular NIRF imaging strategy provides high-resolution in vivo spatial mapping of arterial inflammation in coronary-sized arteries and reveals increased inflammation-regulated cysteine protease activity in atheromata and stent-induced arterial injury.
Journal ArticleDOI
Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve.
Jacob P. Dal-Bianco,Elena Aikawa,Joyce Bischoff,J. Luis Guerrero,Jesper Hjortnaes,Jonathan Beaudoin,Catherine Szymanski,Philipp E. Bartko,Margo M. Seybolt,Mark D. Handschumacher,Suzanne Sullivan,Michael L. Garcia,Adam Mauskapf,James S. Titus,Jill Wylie-Sears,Whitney S. Irvin,Miguel Chaput,Emmanuel Messas,Albert Hagège,Alain Carpentier,Robert A. Levine +20 more
TL;DR: Tethered plus MI findings were comparable with external ventricular constraint, and uniquely, tethering plus MI showed endothelial activation with vascular adhesion molecule expression, neovascularization, and cells positive for CD45, considered a hematopoietic cell marker.
Journal ArticleDOI
Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo
Tetsuya Hara,Giovanni J. Ughi,Jason R. McCarthy,S. Sibel Erdem,Adam Mauskapf,Samantha C. Lyon,Ali Fard,Elazer R. Edelman,Guillermo J. Tearney,Farouc A. Jaffer +9 more
TL;DR: Intravascular NIRF fibrin molecular imaging improves the detection of unhealed stents, using clinically translatable technology that complements OCT, and have implications for the specificity of standalone clinical OCT assessments of stent healing.
Journal ArticleDOI
Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging.
Ashley F. Stein-Merlob,Tetsuya Hara,Jason R. McCarthy,Adam Mauskapf,James A. Hamilton,Vasilis Ntziachristos,Peter Libby,Farouc A. Jaffer +7 more
TL;DR: This article used nanoparticle-enhanced optical molecular imaging to probe in vivo mechanisms involving impaired endothelial barrier function in experimental atherothrombosis using aortic balloon injury and high cholesterol diet.
Journal ArticleDOI
Near Infrared Fluorescence (NIRF) Molecular Imaging of Oxidized LDL with an Autoantibody in Experimental Atherosclerosis
Ramzi Khamis,Kevin J. Woollard,Gareth Hyde,Joseph J. Boyle,Colin Bicknell,Shang-Hung Chang,Talat H. Malik,Tetsuya Hara,Adam Mauskapf,David W Granger,Jason L. Johnson,Vasilis Ntziachristos,Paul M. Matthews,Farouc A. Jaffer,Dorian O. Haskard +14 more
TL;DR: A quantitative antibody-based near infrared fluorescence approach for the imaging of oxidized LDL in atherosclerosis and a partially humanized chimeric LO1-Fab-Cys localized similarly to the parent antibody in murine atheroma showing promise for future translation.