A
Adeeti Ullal
Researcher at Apple Inc.
Publications - 20
Citations - 1770
Adeeti Ullal is an academic researcher from Apple Inc.. The author has contributed to research in topics: Olaparib & Dyskinesia. The author has an hindex of 11, co-authored 20 publications receiving 1544 citations. Previous affiliations of Adeeti Ullal include University of California, Berkeley & Massachusetts Institute of Technology.
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Journal ArticleDOI
Synthetic protein scaffolds provide modular control over metabolic flux
John E. Dueber,Gabriel C. Wu,G Reza Malmirchegini,G Reza Malmirchegini,Tae Seok Moon,Christopher J. Petzold,Christopher J. Petzold,Adeeti Ullal,Kristala L. J. Prather,Jay D. Keasling +9 more
TL;DR: In this article, synthetic protein scaffolds bearing interaction domains from metazoan signaling proteins were used to spatially recruit metabolic enzymes in a designable manner, and the modularity of these domains enabled them to optimize the stoichiometry of three mevalonate biosynthetic enzymes recruited to a synthetic complex.
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Cancer cell profiling by barcoding allows multiplexed protein analysis in fine needle aspirates
Adeeti Ullal,Vanessa M. Peterson,Sarit S. Agasti,Suan Tuang,Dejan Juric,Cesar M. Castro,Ralph Weissleder +6 more
TL;DR: The ABCD platform could help researchers to better understand tumor heterogeneity, as well as allow clinicians to personalize therapies and perhaps even track therapeutic response less invasively, as the authors demonstrated in vitro and in four patients taking kinase inhibitors.
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Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents.
Thomas Reiner,Jessica Lacy,Edmund J. Keliher,Katherine S. Yang,Adeeti Ullal,Rainer H. Kohler,Claudio Vinegoni,Ralph Weissleder +7 more
TL;DR: It is shown that the bioorthogonal (18)F modification of the parent molecule is simple, highly efficient, and well tolerated, resulting in a half maximal inhibitory concentration (IC(50)) of 17.9 ± 1.1 nM.
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Smartwatch inertial sensors continuously monitor real-world motor fluctuations in Parkinson’s disease
Rob Powers,Maryam Etezadi-Amoli,Edith Merle Arnold,Sara Kianian,Sara Kianian,Irida Mance,Maxsim Gibiansky,Dan Marvin Trietsch,Alexander Singh Alvarado,James D. Kretlow,Todd M. Herrington,Salima Brillman,Nengchun Huang,Peter T. Lin,Hung A. Pham,Adeeti Ullal +15 more
TL;DR: The Motor fluctuations Monitor for Parkinson's Disease (MM4PD) as discussed by the authors is an ambulatory monitoring system that used smartwatch inertial sensors to continuously track fluctuations in resting tremor and dyskinesia.
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Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip
TL;DR: A hybrid magnetic/size-sorting (HMSS) chip for isolation and molecular analyses of circulating tumor cells (CTCs) and the study of individual CTCs for heterogeneity in molecular marker expression is presented.