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Adolfo F. Valdes
Researcher at University of Oviedo
Publications - 4
Citations - 255
Adolfo F. Valdes is an academic researcher from University of Oviedo. The author has contributed to research in topics: Epigenome & Epigenetics. The author has an hindex of 4, co-authored 4 publications receiving 168 citations.
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Epigenetics in cancer therapy and nanomedicine.
TL;DR: The importance of the epigenetic alterations identified in human cancer, which have led to the appearance of biomarkers or epigenetic drugs in precision medicine, are summarized, and the transport and release systems of theigenetic drugs that have been developed to date are described.
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The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome
TL;DR: The challenge for the future will be to determine the molecular pathways driving these epigenetic alterations, the possible functional consequences, and the potential effects on health.
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DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes
Marta I. Sierra,Laura Rubio,Gustavo F. Bayón,Isabel Cobo,Pablo Menendez,Paula Morales,Cristina Mangas,Rocío G. Urdinguio,Virginia Lopez,Adolfo F. Valdes,Gerard Vales,Ricard Marcos,Ramón Torrecillas,Agustín F. Fernández,Mario F. Fraga +14 more
TL;DR: The results suggest that long-term MWCNT exposure may have important effects on the epigenome, mainly located at low density CpG regions and enhancers, and very frequently on the X chromosome.
Journal ArticleDOI
No genome-wide DNA methylation changes found associated with medium-term reduced graphene oxide exposure in human lung epithelial cells.
Raúl F. Pérez,Anna Yunuen Soto Fernández,Pablo Bousquets Muñoz,Marta I. Sierra,Juan Ramón Tejedor,Paula Morales-Sánchez,Adolfo F. Valdes,Ricardo Santamaría,Clara Blanco,Ramón Torrecillas,Mario F. Fraga,Agustín F. Fernández +11 more
TL;DR: In this article, the authors presented a study that has been financially supported by: The Plan Nacional de I+D+I co-funding FEDER (PI15/00892 and PI18/01527); the Government of the Principality of Asturias PCTI-Plan de Ciencia, Tecnologia e Innovacion de Asturanias co- funding 2018-2022/FEDER(IDI/2018/146 and IDI/ 2018/121); AECC (PROYE18061