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Adrian M Brooke
Researcher at University of Leicester
Publications - 22
Citations - 1176
Adrian M Brooke is an academic researcher from University of Leicester. The author has contributed to research in topics: Wheeze & Population. The author has an hindex of 14, co-authored 21 publications receiving 1138 citations.
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Journal ArticleDOI
Are all wheezing disorders in very young (preschool) children increasing in prevalence
TL;DR: The fact that all preschool wheezing disorders increased makes it probable that factors unrelated to atopy are implicated in the changing epidemiology of wheeze in childhood.
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Distinguishing phenotypes of childhood wheeze and cough using latent class analysis
TL;DR: Examination of phenotypes of childhood wheeze and chronic cough is examined, by fitting a statistical model to data representing multiple disease dimensions, to identify clinically relevant phenotypes, not only in paediatric disorders but also in adult obstructive airway diseases, where phenotype definition is an equally important issue.
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The natural history of respiratory symptoms in preschool children.
TL;DR: It is shown that fewer than half of preschool wheezy children continued to wheeze in the early school years but those with persistent wheEze display many of the clinical characteristics consistent with a diagnosis of asthma.
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Parental understanding of wheeze and its impact on asthma prevalence estimates.
Gisela Michel,Michael Silverman,M-P. F. Strippoli,Marcel Zwahlen,Adrian M Brooke,Jonathan Grigg,Claudia E. Kuehni +6 more
TL;DR: It was shown that misunderstanding could lead to an important bias in assessing the prevalence of wheeze, resulting in an underestimation in children from South Asian and deprived family backgrounds.
Journal ArticleDOI
Cohort Profile: The Leicester Respiratory Cohorts
Claudia E. Kuehni,Adrian M Brooke,Marie-Pierre F. Strippoli,Ben D. Spycher,Anthony Davis,Michael Silverman +5 more
TL;DR: This data indicates that wheezing during the first trimester of pregnancy may have an important role in the development of asthma and the immune defences of the immune system.