Agata Braniewska

TL;DR: In this paper, a review discusses emerging functions of miRNAs in cardiogenesis, heart regeneration and the pathophysiology of cardiovascular diseases, including myocardial infarction, hypertrophy, fibrosis, heart failure, arrhythmia, inflammation and atherosclerosis.

TL;DR: The phenotype and functional stability of the RAW 264.7 cell line is investigated and it is found that the phenotype (expression of particular macrophage-characteristic genes and surface markers) and functional characteristics (phagocytosis and NO production) of the cell line remains stable through passages.

TL;DR: It is concluded that administration of agonistic anti-CD200R improves the antitumor effects of TLR7 signaling and changes the local tumor microenvironment, which becomes less supportive of tumor progression.

TL;DR: It is found that the expression of IDO, elevated after PDT, affects the polarization of T regulatory cells and influences the innate immune response, and overcoming IDO-induced immunosuppressive mechanisms after PDT can be beneficial or can lead to a systemic toxic reaction.

TL;DR: It is concluded that blockade of the endogenous ligand CD200 prevented the tumorigenic effect of CD200R-expressing myeloid cells in the tumor microenvironment, whereas agonistic anti-CD200R has no effect on tumor development.