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Agneta Holmäng
Researcher at University of Gothenburg
Publications - 94
Citations - 4414
Agneta Holmäng is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 35, co-authored 92 publications receiving 4080 citations. Previous affiliations of Agneta Holmäng include Cardiovascular Institute of the South & Sahlgrenska University Hospital.
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A New Rat Model Exhibiting Both Ovarian and Metabolic Characteristics of Polycystic Ovary Syndrome
Louise Mannerås,Stefan Cajander,Agneta Holmäng,Zamira Seleskovic,Theodore Lystig,Malin Lönn,Elisabet Stener-Victorin +6 more
TL;DR: A new rat PCOS model is described, the first to exhibit both ovarian and metabolic characteristics of the syndrome, and it is suggested that the formation of a "hyperplastic" theca interna reflects the inclusion of luteinized granulosa cells in the cyst wall rather than true hyperplasia.
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Prenatal exposure to interleukin-6 results in inflammatory neurodegeneration in hippocampus with NMDA/GABAA dysregulation and impaired spatial learning
TL;DR: It is suggested that fetal IL-6 exposure, especially in late pregnancy, leads to increased IL- 6 levels in the circulation and hippocampus, abnormalities of hippocampal structural and morphology, and decreased learning during adulthood.
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Interleukin-6 in the Maternal Circulation Reaches the Rat Fetus in Mid-gestation
TL;DR: The permeability of the rat placental barrier to IL-6 is much higher in mid-gestation than in late pregnancy, suggesting that maternally derived IL- 6 may directly induce fetal injury but also stimulate the release of fetal stress hormones which might lead to disease at adult age.
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A randomized longitudinal dietary intervention study during pregnancy: effects on fish intake, phospholipids, and body composition.
Marja Bosaeus,Aysha Hussain,Therese Karlsson,Louise Andersson,Lena Hulthén,Cecilia Svelander,Ann-Sofie Sandberg,Ingrid Larsson,Lars Ellegård,Lars Ellegård,Agneta Holmäng +10 more
TL;DR: Dietary counseling throughout pregnancy could help women increase their fish intake and intake of meat in early pregnancy may increase the gain in fat-free mass during pregnancy.
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Effects of testosterone on muscle insulin sensitivity and morphology in female rats
TL;DR: It was concluded that testosterone administered to female rats is followed by marked insulin resistance, correlated to alterations in muscle morphology with fewer type 1 fibers and a lower degree of capillarization, which are both known to be characteristics of insulin-insensitive muscles.