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Agustina Tri Endharti
Researcher at University of Brawijaya
Publications - 63
Citations - 825
Agustina Tri Endharti is an academic researcher from University of Brawijaya. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 11, co-authored 49 publications receiving 720 citations. Previous affiliations of Agustina Tri Endharti include Magister & Nagoya University.
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Journal ArticleDOI
Cutting Edge: CD8+CD122+ Regulatory T Cells Produce IL-10 to Suppress IFN-γ Production and Proliferation of CD8+ T Cells
Agustina Tri Endharti,Muhaimin Rifa'i,Muhaimin Rifa'i,Zhe Shi,Yukari Fukuoka,Yoshio Nakahara,Yoshiyuki Kawamoto,Yoshiyuki Kawamoto,Kozue Takeda,Ken-ichi Isobe,Haruhiko Suzuki +10 more
TL;DR: Investigation of the effector mechanism of CD8+CD122+ regulatory T cells by using an in vitro regulation system indicates that IL-10 is produced by CD8- CD122+ cells and mediates the regulatory activity of these cells.
Journal ArticleDOI
Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg
Zhe Shi,Yusuke Okuno,Muhaimin Rifa'i,Agustina Tri Endharti,Kazuyuki Akane,Ken-ichi Isobe,Haruhiko Suzuki +6 more
TL;DR: DNA microarray analyses suggest that human CD8+CXCR3+ T cells are the counterparts of murineCD8+CD122+ Treg, and it is suggested that the expression pattern of CD8 and CD122 in humans is different from that in mice.
Journal ArticleDOI
CD8+CD122+ Regulatory T Cells (Tregs) and CD4+ Tregs Cooperatively Prevent and Cure CD4+ Cell-Induced Colitis
Agustina Tri Endharti,Yusuke Okuno,Zhe Shi,Nobuaki Misawa,Shinya Toyokuni,Masafumi Ito,Ken-ichi Isobe,Haruhiko Suzuki +7 more
TL;DR: It is shown that CD8+CD122+ Tregs effectively prevent and cure colitis in a mouse model, and a mixture of CD8-CD122- cells and CD4+CD45RBlow cells was far more effective than single T Regs, indicating the synergistic effect of these TregS.
Journal Article
Vitamin D Prevents Endothelial Damage Induced by Increased Neutrophil Extracellular Traps Formation in Patients with Systemic Lupus Erythematosus
Kusworini Handono,Yona One Sidarta,Benny Arie Pradana,Radhitio Adi Nugroho,Ivan A Hartono,Handono Kalim,Agustina Tri Endharti +6 more
TL;DR: Major decrease in early apoptosis with 10 nM of 1,25(OH)2D3 compared to control group may reveal the possibility of Vitamin D as supplementary therapy for SLE patients with hypovitamin D to prevent endothelial damage.
Journal Article
Effects of 1,25(OH)2D3 in immune response regulation of systemic lupus erithematosus (SLE) patient with hypovitamin D.
Cesarius Singgih Wahono,Hetti Rusmini,Dwi Soelistyoningsih,Reza Hakim,Kusworini Handono,Agustina Tri Endharti,Handono Kalim,Edi Widjajanto +7 more
TL;DR: The study concluded that 1,25(OH)2D3 inhibited dendritic cells maturation and Th17 cells activation in SLE patients.