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Ahmed H. Bakheit
Researcher at King Saud University
Publications - 113
Citations - 1694
Ahmed H. Bakheit is an academic researcher from King Saud University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 19, co-authored 87 publications receiving 891 citations. Previous affiliations of Ahmed H. Bakheit include Neelain University.
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Journal ArticleDOI
Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach.
TL;DR: The fluorescence, UV- absorption, three dimensional fluorescence and FT-IR data showed conformational changes occurred in BSA after interaction with neratinib, suggesting an instable complex formation at high temperature.
Book ChapterDOI
Chapter One – Azithromycin
TL;DR: The present study gives a comprehensive profile of azithromycin, including detailed physico-chemical properties, nomenclature, formulae, methods of preparation, and methods of analysis (including compendial, electrochemical, spectroscopic, and chromatographic methods ofAnalysis).
Journal ArticleDOI
Spectrophotometric and molecular modelling studies on in vitro interaction of tyrosine kinase inhibitor linifanib with bovine serum albumin.
Tanveer A. Wani,Ahmed H. Bakheit,Ahmed H. Bakheit,Seema Zargar,Mohammed A. Hamidaddin,Ibrahim A. Darwish +5 more
TL;DR: The experimental and molecular docking results suggest that the interaction between LNF and BSA was spontaneous and they exhibited hydrogen bonding and van der Waals force between them.
Journal ArticleDOI
Multi-spectroscopic investigation, molecular docking and molecular dynamic simulation of competitive interactions between flavonoids (quercetin and rutin) and sorafenib for binding to human serum albumin.
TL;DR: Serum albumin, the main protein in the plasma acts in the disposition of many drugs and therefore, is a model protein for investigating drug/ligand binding and alteration in the spectrophotometric and molecular docking properties of drug /ligand.
Journal ArticleDOI
Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine serum albumin
Ali S. Abdelhameed,Amer M. Alanazi,Ahmed H. Bakheit,Hany W. Darwish,Hazem A. Ghabbour,Ibrahim A. Darwish +5 more
TL;DR: It can be inferred that hydrophobic and electrostatic interactions are the major binding forces involved in formation of the CRB-BSA complex.