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Ajay J. Kirtane
Researcher at Brigham and Women's Hospital
Publications - 16
Citations - 367
Ajay J. Kirtane is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & Percutaneous coronary intervention. The author has an hindex of 8, co-authored 16 publications receiving 344 citations. Previous affiliations of Ajay J. Kirtane include Beth Israel Deaconess Medical Center & New York University.
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Interventional Cardiology Benefit of Transferring ST-Segment-Elevation Myocardial Infarction Patients for Percutaneous Coronary Intervention Compared With Administration of Onsite Fibrinolytic Declines as Delays Increase
Duane S. Pinto,Paul D. Frederick,Anjan K. Chakrabarti,Ajay J. Kirtane,Edward Ullman,Andre Dejam,Dave P. Miller,Timothy D. Henry,C. Michael Gibson +8 more
TL;DR: In this article, the authors investigated the effect of PCI-related delay on in-hospital mortality and found no mortality advantage for X-PCI over O-FT when XDB door-to-needle time exceeded 120 minutes.
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Association of duration of symptoms at presentation with angiographic and clinical outcomes after fibrinolytic therapy in patients with st-segment elevation myocardial infarction
C. Michael Gibson,Sabina A. Murphy,Ajay J. Kirtane,Ajay J. Kirtane,Robert P. Giugliano,Christopher P. Cannon,Elliott M. Antman,Eugene Braunwald +7 more
TL;DR: A prolonged symptom to treatment time among STEMI patients is associated with impaired myocardial perfusion independent of epicardial flow both immediately after fibrinolytic administration and after rescue/adjunctive PCI, and these data provide a pathophysiologic link between prolonged symptoms due to vessel occlusion, impaired my cardiac perfusion, and poor clinical outcomes.
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Comparison of very early treatment with either fibrinolysis or percutaneous coronary intervention facilitated with abciximab with respect to ST recovery and infarct-related artery epicardial flow in patients with acute ST-segment elevation myocardial infarction: the Swedish Early Decision (SWEDES) reperfusion trial.
Leif Svensson,Mikael Aasa,Mikael Dellborg,C. Michael Gibson,Ajay J. Kirtane,Johan Herlitz,Ake Ohlsson,Thomas Karlsson,Lars Grip +8 more
TL;DR: Despite much shorter time delay to start of fibrinolysis than PCI, this did not result in signs of superior myocardial reperfusion and there was a trend toward better clinical outcome after this treatment compared with after fibralelysis.
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Surgical Versus Percutaneous Coronary Revascularization for Multivessel Disease in Diabetic Patients With Non–ST-Segment–Elevation Acute Coronary Syndrome Analysis From the Acute Catheterization and Early Intervention Triage Strategy Trial
Yanai Ben-Gal,Rephael Mohr,Frederick Feit,E. Magnus Ohman,Ajay J. Kirtane,Ke Xu,R Mehran,Gregg W. Stone +7 more
TL;DR: In the large-scale ACUITY trial, diabetic patients with acute coronary syndrome and multivessel disease treated with PCI rather than CABG had less bleeding and acute kidney injury, greater need for repeat revascularization procedures, and comparable rates of myocardial infarction, stroke, and death through 1-year follow-up.
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Association of the Fibonacci Cascade with the distribution of coronary artery lesions responsible for ST-segment elevation myocardial infarction.
C. Michael Gibson,William J. Gibson,Sabina A. Murphy,Susan J. Marble,Carolyn H. McCabe,Minang Turakhia,Ajay J. Kirtane,Juhana Karha,Julian M. Aroesty,Robert P. Giugliano,Elliott M. Antman +10 more
TL;DR: This is the first study to demonstrate the appearance of the Fibonacci Cascade within the distribution of coronary artery lesions in the human heart.