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Showing papers in "Journal of the American College of Cardiology in 2004"


Journal ArticleDOI
TL;DR: The risk of CIN after PCI can be simply assessed using readily available information and can be used for both clinical and investigational purposes.

2,099 citations


Journal ArticleDOI
TL;DR: Recent experimental and clinical data support the hypothesis that cigarette smoke exposure increases oxidative stress as a potential mechanism for initiating cardiovascular dysfunction.

2,064 citations


Journal ArticleDOI
TL;DR: Testing the hypothesis that complex fractionated electrograms recorded during atrial fibrillation could be used as target sites for catheter ablation of AF found areas with CFAEs represent a defined electrophysiologic substrate and are ideal target Sites for ablations to eliminate AF and maintain normal sinus rhythm.

2,021 citations




Journal ArticleDOI
TL;DR: The growth of understanding of the pulmonary hypertensive diseases that has enabled the development of a clinical classification oriented towards prevention and treatment is traced.

1,795 citations


Journal ArticleDOI
TL;DR: Pulmonary arterial hypertension has a multifactorial pathobiology and recent genetic and pathophysiologic studies have emphasized the relevance of several mediators in this condition, including prostacyclin, nitric oxide, ET-1, angiopoietin- 1, serotonin, cytokines, chemokines, and members of the transforming-growth-factor-beta superfamily.

1,501 citations


Journal ArticleDOI
TL;DR: Multidisciplinary strategies for the management of patients with HF reduce HF hospitalizations and those programs that involve specialized follow-up by a multidisciplinary team also reduce mortality and all-cause hospitalizations.

1,361 citations


Journal ArticleDOI
TL;DR: It is concluded that increasing tricuspid regurgitation severity is associated with worse survival in men regardless of LVEF or pulmonary artery pressure.

1,280 citations


Journal ArticleDOI
TL;DR: Intracoronary infusion of progenitor cells (either BMC or CPC) is safe and feasible in patients after AMI successfully revascularized by stent implantation, suggesting functional regeneration of the infarcted ventricles.

1,117 citations


Journal ArticleDOI
TL;DR: Patients with LV dyssynchrony >/=65 ms respond to CRT and have an excellent prognosis after CRT, and Receiver-operator characteristic curve analysis demonstrated that an optimal cutoff value of 65 ms for LV dySSynchrony yielded a sensitivity and specificity of 80% to predict clinical improvement and of 92% to Predict LV reverse remodeling.

Journal ArticleDOI
TL;DR: It is proposed that sleep loss may be one of the ways that inflammatory processes are activated and contribute to the association of sleep complaints, short sleep duration, and cardiovascular morbidity observed in epidemiologic surveys.

Journal ArticleDOI
TL;DR: Though much has recently been learned about the syndrome of HF-PSF, many questions remain to be answered, not least how it should be treated.

Journal ArticleDOI
TL;DR: Pulmonary arterial hypertension is diagnosed by various investigations that are essential for making the diagnosis, and by additional tests to clarify the category of pulmonary hypertension (PH).

Journal ArticleDOI
TL;DR: A clear ongoing trend toward equalization of the two procedures, in terms of procedural success, is evident through the years, probably due to technologic progress of materials and increased operator experience.

Journal ArticleDOI
TL;DR: Digital hyperemic response, as measured by RH-PAT, is attenuated in patients with coronary microvascular endothelial dysfunction, suggesting a role for RH- PAT as a noninvasive test to identify patients with this disorder.


Journal ArticleDOI
TL;DR: The best long-term predictors of SVG graft patency are grafting into the LAD and grafts into a vessel that is >2.0 mm in diameter, and the 10-year patency of IMA grafts is better than SVGs.

Journal ArticleDOI
TL;DR: Implantation of the PHV can be achieved in patients with end-stage calcific aortic stenosis and might become an important therapeutic option for patients not amenable to surgical valve replacement.

Journal ArticleDOI
TL;DR: Sudden cardiac death accounts for 5.6% of annual mortality, and prospective evaluation in the general population appears to be feasible, and the use of multiple sources of ascertainment and information significantly enhances phenotyping of SCD cases.

Journal ArticleDOI
TL;DR: Adherence to the traditional Mediterranean diet was associated with a reduction in the concentrations of inflammation and coagulation markers, which may partly explain the beneficial actions of this diet on the cardiovascular system.

Journal ArticleDOI
TL;DR: This study demonstrates that, in the case of diagnostic image quality, contrast-enhanced MDCT permits an accurate identification of coronary plaques and that computed tomography density values measured within plaques reflect echogenity and plaque composition.

Journal ArticleDOI
TL;DR: A histopathological classification is proposed that includes both the predominant segment of the pulmonary vasculature affected and the possible coexistence of pathological changes in other vascular segments in PAH.

Journal ArticleDOI
TL;DR: Assessment of the incidence, clinical predictors, and outcome of contrast-induced nephropathy after primary percutaneous coronary intervention for acute myocardial infarction found that preventive strategies are needed, particularly in high-risk patients.

Journal ArticleDOI
TL;DR: Traditional risk factors of a poor clinical outcome and mortality in the general population, including body mass index, serum cholesterol, and blood pressure, are also found to relate to outcome in patients with chronic heart failure, but in an opposite direction.

Journal ArticleDOI
TL;DR: In this patient with HCM and heart failure, regions of myocardial late gadolinium enhancement by CMR represented regions of increased myocardia collagen but not disarray.

Journal ArticleDOI
TL;DR: The occurrence of AF following CABG identifies a subset of patients who have a reduced survival probability following C ABG, and the impact of various strategies, such as antiarrhythmics and warfarin, aimed at reducing AF and its complications deserves further study.

Journal ArticleDOI
TL;DR: In patients with long lesions in small vessels, the SES dramatically reduces the risk of restenosis at eight months, translating into an excellent clinical outcome at nine months.

Journal ArticleDOI
TL;DR: Leukocytosis has been consistently shown to be an independent risk factor and prognostic indicator of future cardiovascular outcomes, regardless of disease status, and the leukocyte count is inexpensive, reliable, easy to interpret, and ordered routinely in inpatient and outpatient settings.

Journal ArticleDOI
TL;DR: Mortality from all causes is increased in asymptomatic patients with diabetes in proportion to the screening CCS, Nonetheless, subjects without coronary artery calcium have a low short-term risk of death even in the presence of diabetes mellitus.