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Showing papers in "American Heart Journal in 2006"


Journal ArticleDOI
TL;DR: In this article, a new bleeding risk scheme, HEMORR 2 HAGES, was proposed to quantify the risk of hemorrhage in elderly patients with atrial fibrillation.

958 citations


Journal ArticleDOI
TL;DR: In patients presenting within 24 hours of the development of CGS, TandemHeart significantly improves hemodynamic parameters, even in patients failing IABP, and larger-scale studies are required to assess the influence of improved hemodynamics on survival.

503 citations


Journal ArticleDOI
TL;DR: Attempts to improve glycemic control reduce the incidence of macrovascular events both in type 1 and type 2 DM, in absolute terms, although effects on specific manifestations of macroVascular disease differ.

475 citations


Journal ArticleDOI
TL;DR: The acuity of the clinical presentation of bare metal ISR appears to be more severe than has been previously thought and aggressive efforts, such as drug-eluting stents to decrease the incidence of unstable angina due to bareMetal ISR, are warranted.

390 citations


Journal ArticleDOI
TL;DR: In this population-based cohort, LA diameter independently predicted incident cardiovascular events after adjustment for established clinical, echocardiographic, and inflammatory risk factors.

358 citations


Journal ArticleDOI
TL;DR: In this article, the authors evaluated the clinical, imaging, and pathology characteristics of confirmed left ventricular thrombus and compared the diagnostic value of contrastenhanced magnetic resonance imaging (MRI) with transthoracic (TTE) and transesophageal echocardiography (TEE) for the diagnosis of LV thrombi.

358 citations


Journal ArticleDOI
TL;DR: The results showed metoprolol was not effective in reducing the 30-day and 6-month postoperative cardiac event rates and prophylactic use of perioperative β -blockers in all vascular patients is not indicated.

347 citations


Journal ArticleDOI
TL;DR: This study will define the roles of CABG and PCI using drug-eluting stents in the contemporary management of LM and 3VD by replacing most traditional inclusion and exclusion criteria with the real-world decision between the cardiothoracic surgeon and the interventionalist.

323 citations



Journal ArticleDOI
TL;DR: It is suggested that intensive periodontal treatment reduces systemic inflammatory markers and systolic BP, and improves lipid profiles with subsequent changes in cardiovascular risk when compared to standard therapy.

312 citations


Journal ArticleDOI
TL;DR: TRITON-TIMI 38 is the first large-scale clinical events trial to assess whether a thienopyridine regimen that achieves a higher level of inhibition of platelet aggregation than the standard therapy results in an improvement in clinical outcomes.

Journal ArticleDOI
TL;DR: A high prevalence of anxiety is found and depression is confirmed in the HF outpatient population and depression and social isolation predicted mortality independent of demographic and clinical status in HF outpatients.

Journal ArticleDOI
TL;DR: Evaluation of gender-specific CRP cut points to determine cardiovascular risk should be considered and this pattern of higher CRP levels in women was consistent across all ethnic subgroups even after multivariable adjustment.

Journal ArticleDOI
TL;DR: A randomized clinical trial contrasting optimum medical therapy alone to stenting with optimum medical Therapy on a composite cardiovascular and renal end point and determining the incremental value of stent revascularization, in addition to optimal medical therapy, for the treatment of atherosclerotic renal artery stenosis.


Journal ArticleDOI
TL;DR: Investigation of the feasibility of using optical coherence tomography (OCT) to measure the thickness of the fibrous cap within lipid-rich plaque found good correlation between OCT and histological examination and good agreement of the thickness was shown.

Journal ArticleDOI
TL;DR: The morbidity related to PPCM is less than previously reported and initial LV end-diastolic dimension and EF at 2 months predict long-term outcomes, while the withdrawal of heart failure medications after recovery did not lead to decompensation.

Journal ArticleDOI
TL;DR: Meta-analysis of the available studies with MRI and MSCT for noninvasive coronary angiography indicates that MSCT has currently a significantly higher accuracy to detect or exclude significant coronary artery disease.

Journal ArticleDOI
TL;DR: The REACH Registry offers an opportunity to provide a better understanding of the prevalence and clinical consequences of atherothrombosis in the outpatient setting in a wide range of patients from different parts of the world.

Journal ArticleDOI
TL;DR: Sildenafil significantly improved the symptomatic status, exercise capacity, NYHA class, and hemodynamic parameters of patients with severe PAH and can be safely used as a primary or adjunctive treatment of the same.

Journal ArticleDOI
TL;DR: Both LVEF and WMSI provide powerful prognostic information after acute myocardial infarction; however, the predictive power of WMSi is greater.

Journal ArticleDOI
TL;DR: In this article, the authors examined patients with coronary artery disease undergoing cardiac catheterization between 1998 and 2001 and found that patients who discontinued medications were more likely to be older, women, unmarried, and less educated.

Journal ArticleDOI
TL;DR: Evidence shows that physician-directed, exercise-based CR positively affects the basic pathophysiology of coronary artery disease, the extent of disability and level of quality of life, and the ability to potentially impact events of both morbidity and mortality.

Journal ArticleDOI
TL;DR: Cardiac CT accurately quantifies LV size and function; RV quantification with cardiac CT requires optimized contrast opacification of the RV.


Journal ArticleDOI
TL;DR: A systematic review of the available literature on factors predicting referral of patients to CR reveals a treatment gap in the secondary prevention of cardiovascular disease.


Journal ArticleDOI
TL;DR: This initial experience with intravenous cangrelor during PCI suggests an acceptable risk of bleeding and adverse cardiac events while achieving rapid, reversible inhibition of platelet aggregation via competitive binding to the ADP P2Y12 platelet receptor with less prolongation of bleeding time then the glycoprotein IIb/IIIa receptor antagonist abciximab.

Journal ArticleDOI
TL;DR: A short-term treatment with antioxidant-rich tomato extract can reduce blood pressure in patients with grade-1 HT, naive to drug therapy, and the continuous effect of this treatment and the long-term beneficial effect on cardiovascular risk factors still need to be demonstrated.