A
Ajeng Diantini
Researcher at Padjadjaran University
Publications - 77
Citations - 576
Ajeng Diantini is an academic researcher from Padjadjaran University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 10, co-authored 56 publications receiving 361 citations.
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Journal ArticleDOI
Kaempferol-3-O-rhamnoside isolated from the leaves of Schima wallichii Korth. inhibits MCF-7 breast cancer cell proliferation through activation of the caspase cascade pathway
Ajeng Diantini,Anas Subarnas,Keri Lestari,Eli Halimah,Yasmiwar Susilawati,Supriyatna,Euis Julaeha,Tri Hanggono Achmad,Eka W. Suradji,Chiho Yamazaki,Kenji Kobayashi,Hiroshi Koyama,Rizky Abdulah +12 more
TL;DR: This study isolated kaempferol-3-O-rhamnoside as an active compound from the leaves of Schima wallichii Korth, a plant commonly consumed by non-human primates, and its anti-cancer activities, including its ability to induce apoptotic mechanisms, were investigated in MCF-7 breast cancer cells.
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Antibiotic resistance in sepsis patients: Evaluation and recommendation of antibiotic use
Ivan S. Pradipta,Dian Chairunnisa Sodik,Keri Lestari,Ida Parwati,Eli Halimah,Ajeng Diantini,Rizky Abdulah +6 more
TL;DR: The high use of antibiotic with a high level resistance requires a policy to support its rational use and local microbial pattern based on site infection and pattern of antibiotics sensitivity test can be used as supporting data to optimize appropriateness of empirical antibiotics therapy in sepsis patients.
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Antiplasmodial properties of kaempferol-3-O-rhamnoside isolated from the leaves of Schima wallichii against chloroquine-resistant Plasmodium falciparum.
Melisa I. Barliana,Eka W. Suradji,Rizky Abdulah,Ajeng Diantini,Toshimitsu Hatabu,Junko Nakajima-Shimada,Anas Subarnas,Hiroshi Koyama +7 more
TL;DR: The present study has provided a basis for the further investigation of kaempferol-3-O-rhamnoside as an active compound for potential antimalarial therapeutics and showed promising antiplasmodial activity against chloroquine-resistant P. falciparum.
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Induction of caspase cascade pathway by kaempferol-3-O-rhamnoside in LNCaP prostate cancer cell lines
Eli Halimah,Ajeng Diantini,Dika P. Destiani,Ivan S. Pradipta,Herri S. Sastramihardja,Keri Lestari,Anas Subarnas,Rizky Abdulah,Hiroshi Koyama +8 more
TL;DR: The results showed that kaempferol-3-O-rhamnoside inhibits the proliferation of LNCaP cells in a dose-dependent manner by upregulating the expression of caspase-8, caspases-9, cospase-3 and poly (ADP-ribose) polymerase proteins.
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Water-soluble propolis and bee pollen of Trigona spp. from South Sulawesi Indonesia induce apoptosis in the human breast cancer MCF-7 cell line.
TL;DR: Water-soluble propolis and bee pollen may have the potential to be elaborated further as a breast anticancer therapy, according to the results from DPPH method of antioxidant assay.