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Ajit J. Shah

Researcher at Middlesex University

Publications -  55
Citations -  1526

Ajit J. Shah is an academic researcher from Middlesex University. The author has contributed to research in topics: High-performance liquid chromatography & Tandem mass spectrometry. The author has an hindex of 19, co-authored 53 publications receiving 1364 citations. Previous affiliations of Ajit J. Shah include University of Westminster & GlaxoSmithKline.

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High-performance liquid chromatography/tandem mass spectrometric assay for the simultaneous measurement of dopamine, norepinephrine, 5-hydroxytryptamine and cocaine in biological samples

TL;DR: A rapid liquid chromatography/tandem mass spectrometry method has been developed for the measurement of dopamine, 5-hydroxytryptamine (5HT) and norepinephrine (NE) in brain microdialysates and the neurotransmitters and cocaine were resolved in a single 4-min run using a binary gradient elution profile.
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Screening for depression among acutely ill geriatric inpatients with a short geriatric depression scale

TL;DR: Both shorter versions of the GDS may be utilized in screening for depression among acutely ill geriatric inpatients.
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Selective antagonism at dopamine D3 receptors enhances monoaminergic and cholinergic neurotransmission in the rat anterior cingulate cortex.

TL;DR: Assessment of the effects of the acute systemic administration of the selective DA D3 receptor antagonist SB-277011-A on the in vivo extracellular levels of monoamines and acetylcholine in the anterior cingulate subregion of the medial prefrontal cortex provides evidence of the important role ofDA D3 receptors in the effect of pharmacotherapeutic agents used for the treatment of psychiatric disorders such as schizophrenia and drug dependence.
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Amino acid neurotransmitters: separation approaches and diagnostic value

TL;DR: In this article, the authors describe the separation and detection techniques that have been used for the measurement of amino acids at trace levels in brain tissue and dialysates and the type of sampling techniques that are used to determine amino acid levels in the brain.
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Increased responsiveness of dopamine to atypical, but not typical antipsychotics in the medial prefrontal cortex of rats reared in isolation.

TL;DR: The increased DA responsiveness to the atypical antipsychotic drugs clozapine and olanzapine may explain the reversal of some of the major behavioral components of the social isolation syndrome, namely hyperactivity and attention deficit.