Rather than enjoying a fine ebook as soon as a mug of coffee in the afternoon, instead they juggled when some harmful virus inside their computer. Methods Of Enzymatic Analysis is clear in our digital library an online admission to it is set as public appropriately you can download it instantly. Our digital library saves in complex countries, allowing you to get the most less latency period to download any of our books considering this one. Merely said, the Methods Of Enzymatic Analysis is universally compatible behind any devices to read.

Methods Of Enzymatic Analysis

Antioxidants: Characterization, natural sources, extraction and analysis

Cancer is a frightful disease and represents one of the biggest health-care issues for the human race and demands a proactive strategy for cure. Plants are reservoirs for novel chemical entities and provide a promising line for research on cancer. Hitherto, being effective, chemotherapy is accompanied by certain unbearable side effects. Nevertheless, plants and plant derived products is a revolutionizing field as these are Simple, safer, eco-friendly, low-cost, fast, and less toxic as compared with conventional treatment methods. Phytochemicals are selective in their functions and acts specifically on tumor cells without affecting normal cells. Carcinogenesis is complex phenomena that involves many signaling cascades. Phytochemicals are considered suitable candidates for anticancer drug development due to their pleiotropic actions on target events with multiple manners. The research is in progress for developing potential candidates (those can block or slow down the growth of cancer cells without any side effects) from these phytochemicals. Many phytochemicals and their derived analogs have been identified as potential candidates for anticancer therapy. Effort has been made through this comprehensive review to highlight the recent developments and milestones achieved in cancer therapies using phytomolecules with their mechanism of action on nuclear and cellular factors. Furthermore, drugs for cancer treatment and their limitations have also been discussed.

https://cyberleninka.org/article/n/127798.pdf

Plant-derived anticancer agents: A green anticancer approach

Neurodegenerative diseases affect not only the life quality of aging populations, but also their life spans. All forms of neurodegenerative diseases have a massive impact on the elderly. The major threat of these brain diseases includes progressive loss of memory, Alzheimer’s disease (AD), impairments in the movement, Parkinson’s disease (PD), and the inability to walk, talk, and think, Huntington’s disease (HD). Oxidative stress and mitochondrial dysfunction are highlighted as a central feature of brain degenerative diseases. Oxidative stress, a condition that occurs due to imbalance in oxidant and antioxidant status, has been known to play a vital role in the pathophysiology of neurodegenerative diseases including AD, PD, and HD. A large number of studies have utilized oxidative stress biomarkers to investigate the severity of these neurodegenerative diseases and medications are available, but these only treat the symptoms. In traditional medicine, a large number of medicinal plants have been used to treat the symptoms of these neurodegenerative diseases. Extensive studies scientifically validated the beneficial effect of natural products against neurodegenerative diseases using suitable animal models. This short review focuses the role of oxidative stress in the pathogenesis of AD, PD, and HD and the protective efficacy of natural products against these diseases.

/pdf/the-role-of-reactive-oxygen-species-in-the-pathogenesis-of-2zsq1lmx8x.pdf

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

THE fact that this text-book by Appleyard and Lyons has made its fourth appearance in ten years is sufficient evidence of its popularity. This new edition differs from its predecessors only by a slightly expanded chapter on qualitative organic analysis.Practical Pharmaceutical ChemistryBy F. N. Appleyard Dr. C. G. Lyons. Fourth edition. Pp. vii + 174. (London: Sir Isaac Pitman and Sons, Ltd., 1939.) 6s. 6d. net.

Practical In Pharmaceutical Chemistry

Urtica dioica L. belongs to the family Urticaceae, is a perennial herb commonly known as ‘stinging nettle’. This herb is found in many South Asian Countries, Indian subcontinent and has been known in the world as a medicinal herb for a long time. U. dioica is widely used by the traditional medicinal practitioners for curing various diseases such as nephritis, haematuria, jaundice, menorrhagia, arthritis and rheumatism. Phytochemical studies revealed the presence of many valuable chemical compounds like phytosterols, saponins, flavanoids, tannins, proteins and amino acids. The plant also has been used as food, fiber, paint, manure and cosmetics. U. dioica has been reported to have various pharmacological activities like antibacterial, antioxidant, analgesic, anti‑inflammatory, antiviral, immunomodulatory, hepatoprotective, anti‑colitis and anticancer effects. The current review summarizes published information about the ethnopharmacology, phytochemistry, biological activities and toxicological reports of U. dioica. The present review summarizes all the research work carried out on this plant in order to provide updated information for future works. Key words: Urtica dioica L., Ethanomedicinal uses, phytochemistry, pharmacology, toxicology

Pharmacognostical review of Urtica dioica L.

Antiepileptic potential of flavonoids fraction from the leaves of Anisomeles malabarica

Background: The objective of the present study was to evaluate the anti-inflammatory activity of aqueous extract of Mirabilis jalapa Linn. (MJL) (Nyctaginaceae) leaves for scientific validation of the folklore claim of the plant. The leaves are used as traditional folk medicine in the south of Brazil to treat inflammatory and painful diseases. Cosmetic or dermo-pharmaceutical compositions containing MJL are claimed to be useful against inflammation and dry skin. Methods: Aqueous extract of the leaves was prepared by cold maceration. Results: The anti-inflammatory activity was evaluated using carrageenan and formalin-induced paw edema models in Wistar albino rats. The anti-inflammatory activity was found to be dose dependent in carrageenan-induced paw edema model. The aqueous extract has shown significant ( P th hour at the doses of 200 and 400 mg/kg, respectively. Similar pattern of paw edema inhibition was seen in formalin-induced paw edema model. The maximum percentage inhibition in paw edema was 32.9% and 43.0% on 4 th day at the doses of 200 and 400 mg/kg, respectively. Conclusion: The results of present study demonstrate that aqueous extract of the leaves possess significant ( P

/pdf/anti-inflammatory-activity-of-aqueous-extract-of-mirabilis-1wr0y2x0lk.pdf

Anti-inflammatory Activity of Aqueous extract of Mirabilis jalapa Linn. Leaves

Multifactorial metabolic diseases, for instance diabetes develop several complications like hyperlipidemia, hepatic toxicity, immunodeficiency etc., Hence, instead of mono-drug therapy the management of the disease requires the combination of herbs. Marketed herbal drugs comprise of irrational combinations, which makes their quality control more difficult. Phytoconstituents, despite having excellent bioactivity in vitro demonstrate less or no in vivo actions due to their poor lipid solubility, resulting in high therapeutic dose regimen; phospholipids encapsulation can overcome this problem. Hence, present study was designed to develop a phospholipids encapsulated polyherbal anti-diabetic formulation. In the present study, polyherbal formulation comprises of lyophilized hydro-alcoholic (50% v/v) extracts of Momordica charantia, Trigonella foenum-graecum and Withania somnifera 2:2:1, respectively, named HA, optimized based on oral glucose tolerance test model in normal Wistar rats. The optimized formulation (HA) entrapped in the phosphatidylcholine and cholesterol (8:2) vesicle system is named HA lipids (HAL). The vesicles were characterized for shape, morphology, entrapment efficiency, polar-dispersity index and release profile in the gastric pH. The antidiabetic potential of HA, marketed polyherbal formulation (D-fit) and HAL was compared in streptozotocin-induced diabetic rat model of 21 days study. The parameters evaluated were behavioral changes, body weight, serum glucose level, lipid profile and oxidative stress. The antidiabetic potential of HA (1000 mg/kg) was at par with the D-fit (1000 mg/kg). However, the potential was enhanced by phospholipids encapsulation; as HAL (500 mg/kg) has shown more significant (P < 0.05) potential in comparison to HA (1000 mg/kg) and at par with metformin (500 mg/kg).

Development of polyherbal antidiabetic formulation encapsulated in the phospholipids vesicle system

Synergistic hepatoprotective potential of ethanolic extract of Solanum xanthocarpum and Juniperus communis against paracetamol and azithromycin induced liver injury in rats.

Ajudhia Nath Kalia

Papers

Pharmacognostical review of Urtica dioica L.

Antiepileptic potential of flavonoids fraction from the leaves of Anisomeles malabarica

Anti-inflammatory Activity of Aqueous extract of Mirabilis jalapa Linn. Leaves

Development of polyherbal antidiabetic formulation encapsulated in the phospholipids vesicle system

Synergistic hepatoprotective potential of ethanolic extract of Solanum xanthocarpum and Juniperus communis against paracetamol and azithromycin induced liver injury in rats.