A
Akihiko Takasaki
Researcher at Gifu University of Medical Science
Publications - 23
Citations - 609
Akihiko Takasaki is an academic researcher from Gifu University of Medical Science. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 13, co-authored 23 publications receiving 570 citations. Previous affiliations of Akihiko Takasaki include Fujita Health University & Gifu University.
Papers
More filters
Journal ArticleDOI
An expression system of rat calmodulin using T7 phage promoter in Escherichia coli.
TL;DR: This system facilitates the large amount preparation of calmodulin and the mutant proteins required for the structural analysis by NMR spectrometry and/or X-ray crystallography.
Journal ArticleDOI
Comprehensive screening for antigens overexpressed on carcinomas via isolation of human mAbs that may be therapeutic
Gene Kurosawa,Yasushi Akahori,Miwa Morita,Mariko Sumitomo,Noriko Sato,Chiho Muramatsu,Keiko Eguchi,Kazuki Matsuda,Akihiko Takasaki,Miho Tanaka,Yoshitaka Iba,Susumu Hamada-Tsutsumi,Yoshinori Ukai,Mamoru Shiraishi,Kazuhiro Suzuki,Maiko Kurosawa,Sally Fujiyama,Nobuhiro Takahashi,Ryoichi Kato,Yoshikazu Mizoguchi,Mikihiro Shamoto,Hiroyuki Tsuda,Mototaka Sugiura,Yoshinobu Hattori,Shuichi Miyakawa,Ryoichi Shiroki,Kiyotaka Hoshinaga,Nobuhiro Hayashi,Atsushi Sugioka,Yoshikazu Kurosawa +29 more
TL;DR: It is likely that some of the Ags detected will become useful targets for the corresponding carcinoma therapy and that several mAbs will become therapeutic agents.
Journal ArticleDOI
Identification of the Calmodulin-binding Domain of Neuron-specific Protein Kinase C Substrate Protein CAP-22/NAP-22 DIRECT INVOLVEMENT OF PROTEIN MYRISTOYLATION IN CALMODULIN-TARGET PROTEIN INTERACTION
TL;DR: In this article, it was shown that CAP-23/NAP-22 isolated from rat brain is myristoylated and that the modification is directly involved in its interaction with calmodulin.
Journal ArticleDOI
Spirostanols obtained by cyclization of pseudosaponin derivatives and comparison of anti-platelet agglutination activities of spirostanol glycosides
Akihiko Tobari,Mutsumi Teshima,Jyunichi Koyanagi,Masami Kawase,Hiroshi Miyamae,Kenji Yoza,Akihiko Takasaki,Yoich Nagamura,Setsuo Saito +8 more
TL;DR: The mechanisms of ring-closure reaction of the side chain at C-22 of pseudosapogenins and pseudosaponins were deduced using stereomodels of the spirostanols derived from 11 under various reaction conditions.
Patent
Method of classifying antigen, method of identifying antigen, method of obtaining antibody or antibody set, method of constructing antibody panel and antibody or antibody set and use of the same
Atsushi Sugioka,Mototaka Sugiura,Yasushi Akahori,Nobuhiro Hayashi,Akihiko Takasaki,Miwa Morita,Gene Kurosawa,Mariko Sumitomo,Susumu Tsutsumi,Keiko Ogawa,Kazuki Matsuda,Chiho Muramatsu,Noriko Satou,Masachika Azuma,Yoshinori Ukai,Kazuhiro Suzuki,Yoshikazu Kurosawa,Miho Tanaka,Mamoru Shiraishi +18 more
TL;DR: In this paper, the authors proposed a method to classify a plural number of antibodies against cell surface antigens and to provide a method for identifying the antigen of the thus classified antibodies.