A
Akshaya Tatke
Researcher at University of Mississippi
Publications - 9
Citations - 250
Akshaya Tatke is an academic researcher from University of Mississippi. The author has contributed to research in topics: Drug delivery & In vivo. The author has an hindex of 6, co-authored 8 publications receiving 171 citations. Previous affiliations of Akshaya Tatke include University of Tennessee Health Science Center.
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Journal ArticleDOI
In Situ Gel of Triamcinolone Acetonide-Loaded Solid Lipid Nanoparticles for Improved Topical Ocular Delivery: Tear Kinetics and Ocular Disposition Studies.
Akshaya Tatke,Narendar Dudhipala,Karthik Yadav Janga,Sai Prachetan Balguri,Bharathi Avula,Monica M. Jablonski,Soumyajit Majumdar +6 more
TL;DR: The results demonstrate that the lipid based nanoparticulate system combined with the in situ gelling agents can be a promising drug delivery platform for the deeper ocular tissues.
Journal ArticleDOI
Ion-sensitive in situ hydrogels of natamycin bilosomes for enhanced and prolonged ocular pharmacotherapy: in vitro permeability, cytotoxicity and in vivo evaluation.
Karthik Yadav Janga,Akshaya Tatke,Sai Prachetan Balguri,Surya P Lamichanne,Mohamed M. Ibrahim,Doaa Nabih Maria,Doaa Nabih Maria,Monica M. Jablonski,Soumyajit Majumdar +8 more
TL;DR: The superior mean dose normalized NT levels in the ocular tissues of rabbits treated with optimized NB and IG illustrated the effectiveness of bilosomes loaded ion-sensitive in situ hydrogels as a potential platform for the improved and prolonged ocular pharmacotherapy.
Journal ArticleDOI
Advances in the use of prodrugs for drug delivery to the eye.
TL;DR: The application of prodrug strategies provides an option for enhancing drug penetration into the ocular tissues, and overall ocular bioavailability, with minimum disruption of the Ocular diffusion barriers.
Journal ArticleDOI
Gellan Gum Based Sol-to-Gel Transforming System of Natamycin Transfersomes Improves Topical Ocular Delivery.
Karthik Yadav Janga,Akshaya Tatke,Narendar Dudhipala,Sai Prachetan Balguri,Mohamed M. Ibrahim,Doaa Nabih Maria,Monica M. Jablonski,Soumyajit Majumdar +7 more
TL;DR: The ocular disposition studies of NT in New Zealand male albino rabbits demonstrated the superiority of the electrolyte-sensitive FNGs in terms of NT delivery to the ocular tissues, and the in situ gelling system of NT from these formulations was significantly higher than in the control suspension.
Journal ArticleDOI
Melt-Cast Noninvasive Ocular Inserts for Posterior Segment Drug Delivery
Sai Prachetan Balguri,Goutham R. Adelli,Akshaya Tatke,Karthik Yadav Janga,Prakash Bhagav,Soumyajit Majumdar +5 more
TL;DR: The melt-cast ophthalmic inserts show promise as an effective noninvasive ocular drug delivery platform, which will be highly beneficial in the intervention and treatment of a wide variety of ocular complications.